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1.发明公开THIAZOLOPYRIMIDINES AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY 有权噻唑并嘧啶及其作为趋化因子受体活性调节剂
公开(公告)号：EP1257556A1
公开(公告)日：2002-11-20
申请号：EP01906447.6
申请日：2001-02-07
申请人： AstraZeneca AB
发明人： BONNERT, Roger , CAGE, Peter , HUNT, Fraser , JEWELL, Robert , WALTERS, Iain
IPC分类号： C07D513/04 , A61K31/519 , A61P11/00 , A61P17/06 , A61P29/00
CPC分类号： C07D513/04
摘要： The invention provides certain thiazolopyrimidine compounds, processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy.
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2.发明授权THIAZOLOPYRIMIDINES AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY 有权噻唑并嘧啶及其作为趋化因子受体活性调节剂
公开(公告)号：EP1257556B1
公开(公告)日：2004-06-16
申请号：EP01906447.6
申请日：2001-02-07
申请人： AstraZeneca AB
发明人： BONNERT, Roger , CAGE, Peter , HUNT, Fraser , JEWELL, Robert , WALTERS, Iain
IPC分类号： C07D513/04 , A61K31/519 , A61P11/00 , A61P17/06 , A61P29/00
CPC分类号： C07D513/04
摘要： The invention provides certain thiazolopyrimidine compounds, processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy.
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公开(公告)号：EP1104425B1
公开(公告)日：2003-01-29
申请号：EP99943554.8
申请日：1999-08-03
申请人： AstraZeneca AB
发明人： AUSTIN, Rupert , BAXTER, Andrew , BONNERT, Roger , HUNT, Fraser , KINCHIN, Elizabeth , WILLIS, Paul
IPC分类号： C07D513/04 , A61K31/519 , A61K31/426 , A61P17/06 , A61P29/00
CPC分类号： C07D513/04
摘要： The invention provides certain thiazolopyrimidine compounds of general formula (I), processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译： 本发明提供了通式（I）的某些噻唑并嘧啶化合物，其制备中使用的方法和中间体，含有它们的药物组合物以及它们在治疗中的用途。
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公开(公告)号：EP1999130A1
公开(公告)日：2008-12-10
申请号：EP07747954.1
申请日：2007-03-20
申请人： AstraZeneca AB
发明人： AUSTIN, Rupert , BONNERT, Roger , HUNT, Fraser , NIKITIDIS, Grigorios , SANGANEE, Hitesh , SJÖ, Peter , WARNER, Dan
IPC分类号： C07D471/04 , A61K31/519 , A61P29/00 , A61P37/02 , C07D519/00
CPC分类号： C07D471/04 , C07D519/00
摘要： The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a PDE 4 mediated disease state.
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5.发明公开PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY 审中-公开嘧啶化合物及其作为趋化因子受体活性调节剂的使用
公开(公告)号：EP1265899A1
公开(公告)日：2002-12-18
申请号：EP01902950.3
申请日：2001-02-07
申请人： AstraZeneca AB
发明人： BONNERT, Roger , CAGE, Peter , HUNT, Fraser , WALTERS, Lain , WILLIS, Paul
IPC分类号： C07D487/04 , A61K31/519 , A61P11/00 , A61P17/06 , A61P29/00
CPC分类号： C07D473/24
摘要： The invention provides certain heterocyclic compounds, processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy; in formula (I), A is a group of formula (a) or (b).
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公开(公告)号：EP1104425A1
公开(公告)日：2001-06-06
申请号：EP99943554.8
申请日：1999-08-03
申请人： AstraZeneca AB
发明人： AUSTIN, Rupert , BAXTER, Andrew , BONNERT, Roger , HUNT, Fraser , KINCHIN, Elizabeth , WILLIS, Paul
IPC分类号： C07D513/04 , A61K31/519 , A61K31/426 , A61P17/06 , A61P29/00
CPC分类号： C07D513/04
摘要： The invention provides certain thiazolopyrimidine compounds of general formula (I), processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy.
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