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公开(公告)号:EP1687336A2
公开(公告)日:2006-08-09
申请号:EP04819225.6
申请日:2004-11-26
申请人: AstraZeneca AB , Dyax Corp.
发明人: NORDSTEDT, Christer, c/o AstraZeneca AB , GOLDSCHMIDT, Tom, c/o AstraZeneca AB , HENDERIKX, Maria , HOET, René , HOOGENBOOM, Hendricus , HUFTON, Simon , ANDERSSON, Christin, V., c/o AstraZeneca AB , LINDQUIST, Johanna, c/o AstraZeneca AB , SUNNEMARK, Dan, c/o AstraZeneca AB , LEONOV, Sergy, c/o AstraZeneca AB
IPC分类号: C07K16/00
CPC分类号: C07K16/18 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/92 , C07K2319/00
摘要: A human antibody fragment, which antibody or fragment: (i) binds to a polypeptide having the amino acid sequence shown in SEQ ID NO: 1 of the C-terminal domain of Apolipoprotein E (ApoE-CTD) or the amino acid sequence of a part thereof; and (ii) binds to human plaques.