公开(公告)号：EP1677788A1

公开(公告)日：2006-07-12

申请号：EP04795637.0

申请日：2004-10-20

申请人： AstraZeneca AB ,  NPS PHARMACEUTICALS, INC.

发明人： BACH, Peter, AstraZeneca R & D Molndal ,  BAUER, Udo, AstraZeneca R & D Molndal ,  NILSSON, Karolina, AstraZeneca R & D Molndal ,  WALLBERG, Andreas, AstraZeneca R & D Molndal

IPC分类号： A61K31/44 ,  C07D213/30 ,  C07D213/61 ,  A61P1/04

CPC分类号： C07D213/30 ,  C07D213/61

摘要： The present invention is directed to novel compounds of formula 1, to a process, for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds. The novel compounds are useful in therapy, and in particular for the treatment 5 of gastroesophageal reflux disease (GERD).