公开(公告)号：EP1981515A2

公开(公告)日：2008-10-22

申请号：EP07762457.5

申请日：2007-01-23

申请人： Athersys, Inc. ,  Medical College of Georgia Research Institute, Inc

发明人： MAYS, Robert W. ,  DEANS, Robert J. ,  HESS, David C. ,  CARROLL, James E. ,  BORLONGAN, Cesar V.

IPC分类号： A61K35/50 ,  A61P9/10

CPC分类号： A61K35/545 ,  A61K38/13 ,  A61K45/06 ,  C12N5/0607 ,  A61K2300/00

摘要： The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.

公开(公告)号：EP1981515B1

公开(公告)日：2013-04-24

申请号：EP07762457.5

申请日：2007-01-23

申请人： Athersys, Inc. ,  Medical College of Georgia Research Institute, Inc

发明人： MAYS, Robert W. ,  DEANS, Robert J. ,  HESS, David C. ,  CARROLL, James E. ,  BORLONGAN, Cesar V.

IPC分类号： A61K35/50 ,  A61P9/10

CPC分类号： A61K35/545 ,  A61K38/13 ,  A61K45/06 ,  C12N5/0607 ,  A61K2300/00

摘要： The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.