公开(公告)号：EP2928460A1

公开(公告)日：2015-10-14

申请号：EP13860898.9

申请日：2013-06-21

申请人： Aurin Biotech Inc.

发明人： MCGEER, Patrick, L. ,  LEE, Moonhee ,  BELL, Douglas, N.

IPC分类号： A61K31/194 ,  A61P17/00

CPC分类号： A61K31/194 ,  A61K9/0014 ,  A61K9/06 ,  A61K47/10 ,  A61K47/46 ,  A61K2300/00

摘要： Methods of treating inflammatory skin conditions comprising topically administering a therapeutically effective amount of aurin tricarboxylic acid (ATA), aurin quadracarboxylic acid (AQA), aurin hexacarboxylic acid (AHA), or a combination thereof are provided. The inflammatory skin conditions may include acne vulgaris, allergic dermatitis, alopecia areata, androgenetic alopecia, atopic dermatitis, dandruff, dermatitis herpetiformis, discoid lupus erythematosus, pemphigus, primary cicatricial alopecia, psoriasis, seborrheic dermatitis, and ultraviolet and thermal burns.

公开(公告)号：EP2928460B1

公开(公告)日：2017-12-27

申请号：EP13860898.9

申请日：2013-06-21

申请人： Aurin Biotech Inc.

发明人： MCGEER, Patrick, L. ,  LEE, Moonhee ,  BELL, Douglas, N.

IPC分类号： A61K9/06 ,  A61K9/08 ,  A61K31/194 ,  A61K47/10 ,  A61K47/46 ,  A61P17/00 ,  A61P17/02 ,  A61P17/04 ,  A61P17/06 ,  A61P17/08 ,  A61P17/10 ,  A61P17/14

CPC分类号： A61K31/194 ,  A61K9/0014 ,  A61K9/06 ,  A61K47/10 ,  A61K47/46 ,  A61K2300/00

摘要： This invention describes a method of preventing and treating inflammatory skin diseases by topical application of aurin tricarboxylic acid and its derivatives. Such diseases are characterized by immune attack, especially involving aberrant complement activation. The diseases include, but are not limited to, androgenetic alopecia (baldness), seborrheic dermatitis/dandruff, allergic dermatitis, primary cicatricial alopecia, pemphigus, psoriasis, discoid lupus erythematosis, and dermatitus herpetiformis.