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1.发明公开MERCAPTOACETYLAMIDE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE 有权MERCAPTOACETYLAMID衍生物，以制作工艺及其用途
公开(公告)号：EP1381605A1
公开(公告)日：2004-01-21
申请号：EP02732549.7
申请日：2002-04-03
发明人： FLYNN, Gary, A. , MEHDI, Shujaath , KOEHL, Jack, Roger , ANDERSON, Barbara, Ann , GERKEN, Manfred , JABLONKA, Bernd , KLEEMANN, Heinz-Werner , LINZ, Wolfgang , SEIZ, Werner , SEURING, Bernhard
IPC分类号： C07D471/04 , A61K31/55 , A61P9/04
CPC分类号： C07D471/04
摘要： This invention discloses and claims a series of mercaptoacetylamide derivatives of formula (I). Also disclosed and claimed are pharmaceutical compositions incorporating these compounds and processes for preparing said compounds. The use of said compounds for inhibition of the enzymes angiotensin converting enzyme and neutral endopeptidase, and for the treatment of hypertension and congestive heart failure are also disclosed and claimed.
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2.发明授权MERCAPTOACETYLAMIDE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE 有权MERCAPTOACETYLAMID衍生物，以制作工艺及其用途
公开(公告)号：EP1381605B1
公开(公告)日：2005-01-12
申请号：EP02732549.7
申请日：2002-04-03
发明人： FLYNN, Gary, A. , MEHDI, Shujaath , KOEHL, Jack, Roger , ANDERSON, Barbara, Ann , GERKEN, Manfred , JABLONKA, Bernd , KLEEMANN, Heinz-Werner , LINZ, Wolfgang , SEIZ, Werner , SEURING, Bernhard
IPC分类号： C07D471/04 , A61K31/55 , A61P9/04
CPC分类号： C07D471/04
摘要： This invention discloses and claims a series of mercaptoacetylamide derivatives of formula (I). Also disclosed and claimed are pharmaceutical compositions incorporating these compounds and processes for preparing said compounds. The use of said compounds for inhibition of the enzymes angiotensin converting enzyme and neutral endopeptidase, and for the treatment of hypertension and congestive heart failure are also disclosed and claimed.
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