公开(公告)号：EP1639139B1

公开(公告)日：2011-07-27

申请号：EP04767370.2

申请日：2004-06-17

申请人： Aventis Pharma S.A.

发明人： MACE, Sandrine ,  RICARD, Sylvain ,  COUSIN, Emmanuelle ,  PRADIER, Laurent ,  BENAVIDES, Jesus ,  DELEUZE, Jean-François

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q2600/156

摘要： The invention relates to methods for the diagnosis or prognosis of Alzheimer's disease in an individual. An inventive method has at least one step for detecting the presence or the absence of the minority allele of polymorphism rs908832 of gene ABCA2. The presence of the minority allele of polymorphism rs908832 of gene ABCA2 indicates that the individual can be afflicted with Alzheimer's disease or is presently at increased risk of developing Alzheimer's disease.

公开(公告)号：EP1639139A2

公开(公告)日：2006-03-29

申请号：EP04767370.2

申请日：2004-06-17

申请人： Aventis Pharma S.A.

发明人： MACE, Sandrine ,  RICARD, Sylvain ,  COUSIN, Emmanuelle ,  PRADIER, Laurent ,  BENAVIDES, Jesus ,  DELEUZE, Jean-François

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q2600/156

摘要： The invention relates to methods for the diagnosis or prognosis of Alzheimer's disease in an individual. An inventive method has at least one step for detecting the presence or the absence of the minority allele of polymorphism rs908832 of gene ABCA2. The presence of the minority allele of polymorphism rs908832 of gene ABCA2 indicates that the individual can be afflicted with Alzheimer's disease or is presently at increased risk of developing Alzheimer's disease.