专利检索 ap:("Aventis Pharma S.A." OR "Genentech, Inc.") AND inv:"CARNIATO, Denis,Résidence Le Samoa Entrée B" 第 1 页

1.

发明公开
DERIVES D'IMINOGUANIDINES, LEUR PROCEDE DE PREPARATION, LEUR APPLICATION COMME MEDICAMENTS 有权
标题翻译： IMINOGUANIDINE衍生物，生产与应用，药物

公开(公告)号：EP1133476A1

公开(公告)日：2001-09-19

申请号：EP99956122.8

申请日：1999-11-23

申请人： Aventis Pharma S.A. , Genentech, Inc.

发明人： CARNIATO, Denis,Résidence Le Samoa Entrée B , GADEK, Thomas, R. , GOURVEST, Jean-François , KNOLLE, Jochen , PEYMAN, Anurschirwan , RUXER, Jean-Marie , BODARY, Sarah, C.

IPC分类号： C07D233/52 , C07C281/18 , A61K31/4168 , A61K31/155 , A61P19/10

CPC分类号： C07C281/18 , C07D233/52

摘要： The invention concerns compounds of formula (I) wherein: m = 1, 2 or 3; n = 1, 2 or 3; R5 represents a group selected among COR6, CO2R6, SO2R6, SO2NHR6, SO2NHCOR6, SO2NHCO2R6, CONH2, CONHR6; R1, R2, R4, R6, R7 R8 and R12 are as defined in the description, in all their possible isomeric forms, their physiologically acceptable salts, their prodrugs. The invention also concerns the method for preparing them, their use as medicines in particular for treating osteoporosis and the pharmaceutical compositions containing them.