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1.发明授权ARGININE VASOPRESSIN PRO-HORMONE AS PREDICTIVE BIOMARKER FOR DIABETES 有权ARGININE VASOPRESSIN PRO-HORMONE作为糖尿病的预测生物标志物
公开(公告)号：EP2356463B1
公开(公告)日：2017-08-30
申请号：EP09744978.9
申请日：2009-10-29
发明人： STRUCK, Joachim , BERGMANN, Andreas , MELANDER, Olle , NEWTON-CHEH, Christopher , WANG, Thomas J.
IPC分类号： G01N33/68
CPC分类号： G01N33/74 , C07K7/16 , G01N33/577 , G01N33/68 , G01N2410/04 , G01N2800/04 , G01N2800/042
摘要： Subject of the present invention are assays and in vitro methods for the prediction of the risk of a subject for contracting metabolic syndrome and/or diabetes mellitus and for diagnosing metabolic syndrome, comprising determining the level of arginine vasopressin pro-hormone or fragments thereof in a sample of a subject.
摘要翻译： 本发明的主题是用于预测受试者感染代谢综合征和/或糖尿病以及用于诊断代谢综合征的风险的测定法和体外方法，其包括测定精氨酸加压素前激素或其片段在 样本的主题。
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公开(公告)号：EP2353011B1
公开(公告)日：2020-03-04
申请号：EP09736845.0
申请日：2009-10-07
发明人： BERGMANN, Andreas , STRUCK, Joachim , MELANDER, Olle , NEWTON-CHEH, Christopher , WANG, Thomas J
IPC分类号： G01N33/68 , G01N33/574 , G01N33/74
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公开(公告)号：EP2841949B1
公开(公告)日：2017-11-22
申请号：EP13717432.2
申请日：2013-04-12
申请人： B.R.A.H.M.S GmbH
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , G01N2800/322 , G01N2800/52
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公开(公告)号：EP2583103B1
公开(公告)日：2016-04-20
申请号：EP11726354.1
申请日：2011-06-17
申请人： B.R.A.H.M.S GmbH
IPC分类号： G01N33/574
CPC分类号： G01N33/6893 , G01N33/574 , G01N2333/575 , G01N2333/5757 , G01N2333/58 , G01N2800/50 , G01N2800/52
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公开(公告)号：EP2583103A1
公开(公告)日：2013-04-24
申请号：EP11726354.1
申请日：2011-06-17
申请人： B.R.A.H.M.S GmbH
IPC分类号： G01N33/574
CPC分类号： G01N33/6893 , G01N33/574 , G01N2333/575 , G01N2333/5757 , G01N2333/58 , G01N2800/50 , G01N2800/52
摘要： Subject of the present invention is a method of assessing the susceptibility of a subject to acquire cancer and/ or assessing the risk of cancer mortality for a subject, who has not had clinically manifest cancer and/or does not have clinically manifest cancer at the time when applying this method.
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6.发明公开ARGININE VASOPRESSIN PRO-HORMONE AS PREDICTIVE BIOMARKER FOR DIABETES 有权ARGININ-VASOPRESSIN-PROHORMON ALS VORHERSAGENDER BIOMARKERFÜRDIABETES
公开(公告)号：EP2356463A1
公开(公告)日：2011-08-17
申请号：EP09744978.9
申请日：2009-10-29
申请人： B.R.A.H.M.S GmbH
发明人： STRUCK, Joachim , BERGMANN, Andreas , MELANDER, Olle , NEWTON-CHEH, Christopher , WANG, Thomas J.
IPC分类号： G01N33/68
CPC分类号： G01N33/74 , C07K7/16 , G01N33/577 , G01N33/68 , G01N2410/04 , G01N2800/04 , G01N2800/042
摘要： Subject of the present invention are assays and in vitro methods for the prediction of the risk of a subject for contracting metabolic syndrome and/or diabetes mellitus and for diagnosing metabolic syndrome, comprising determining the level of arginine vasopressin pro-hormone or fragments thereof in a sample of a subject.
摘要翻译： 本发明的主题是用于预测受试者感染代谢综合征和/或糖尿病并用于诊断代谢综合征的风险的测定和体外方法，包括测定精氨酸加压素原激素或其片段的水平 一个科目的样本。
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7.发明公开BIOMARKERS FOR THE DIAGNOSIS, PROGNOSIS, ASSESSMENT AND THERAPY STRATIFICATION OF SYNCOPE 有权生物识别器ZUR THERAPEUTISCHEN SCHICHTUNG VON SYNKOPEN
公开(公告)号：EP2841949A1
公开(公告)日：2015-03-04
申请号：EP13717432.2
申请日：2013-04-12
申请人： B.R.A.H.M.S GmbH
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , G01N2800/322 , G01N2800/52
摘要： The present invention relates to a method for the diagnosis and/or prognosis and/or assessment and/or therapy stratification of syncope in a patient the method comprising: determining the level of at least one biomarker selected from the group consisting of proET-1, pro ADM, proANP, proBNP, proAVP and PCT or a fragment of at least 12 amino acids thereof, in a sample of a bodily fluid of said patient, correlating said level of at least one biomarker or fragments thereof with the diagnosis and/or prognosis and/or assessment and/or therapy stratification of syncope.
摘要翻译： 本发明涉及一种用于诊断和/或预后和/或评估和/或治疗患者晕厥的治疗方法，所述方法包括：确定至少一种选自以下的生物标志物的水平：proADM，proANP， proBNP，proAVP，proET-1和PCT或其至少12个氨基酸的片段，在所述患者的体液样品中，将所述至少一种生物标志物或其片段的水平与诊断和/或预后相关联，以及 /或评估和/或治疗晕厥分层。
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8.发明公开BIOMARKER FOR THE PREDICTION OF FIRST ADVERSE EVENTS 审中-公开生物标记ZUR VORHERSAGE ERSTER NEGATIVER EREIGNISSE
公开(公告)号：EP2353011A1
公开(公告)日：2011-08-10
申请号：EP09736845.0
申请日：2009-10-07
申请人： B.R.A.H.M.S GmbH
发明人： BERGMANN, Andreas , STRUCK, Joachim , MELANDER, Olle , NEWTON-CHEH, Christopher , WANG, Thomas J
IPC分类号： G01N33/68 , G01N33/574 , G01N33/74
CPC分类号： G01N33/6893 , G01N2800/324 , G01N2800/50
摘要： Subject of the present invention are assays and in vitro methods for the prediction of first coronary and cardiovascular events and biomarkers useful therein.
摘要翻译： 本发明的主题是用于预测第一冠状动脉和心血管事件的测定和体外方法以及在其中有用的生物标志物。
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