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公开(公告)号：EP2643363B1
公开(公告)日：2017-05-31
申请号：EP11843266.5
申请日：2011-11-21
申请人： BASF SE
IPC分类号： C08F126/06
CPC分类号： C08F126/06
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2.发明公开
公开(公告)号：EP2349218A1
公开(公告)日：2011-08-03
申请号：EP09783669.6
申请日：2009-10-02
申请人： BASF SE
发明人： KOLTER, Karl , MASCHKE, Angelika
CPC分类号： A61K9/1694 , A61K9/1635 , A61K9/2027
摘要： The invention relates to a method for producing solid, oral dosage forms with a controlled release of active ingredients. Said forms contain a mixture of a) at least one active ingredient, and b) a pre-formulated mixture of polyvinyl acetate and polyvinyl pyrrolidone, said mixture being obtained by combining components a) and b) in an extruder at temperatures of between 50° and 200°C.
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3.发明授权PHARMAZEUTISCHE FORMULIERUNG FÜR DIE HERSTELLUNG VON SCHNELL ZERFALLENDEN TABLETTEN 有权PHARMAZEUTISCHE FORMULIERUNGFÜRDIE HERSTELLUNG VON SCHNELL ZERFALLENDEN TABLETTEN
公开(公告)号：EP2164462B1
公开(公告)日：2017-05-31
申请号：EP08760389.0
申请日：2008-06-03
申请人： BASF SE
CPC分类号： A61K9/2018 , A61K9/0056 , A61K9/2027 , A61K9/2054
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4.发明授权VERWENDUNG VON COPOLYMEREN AUF BASIS VON POLYETHERN UND VINYLMONOMEREN ALS BINDEMITTEL FÜR FESTE WIRKSTOFFHALTIGE DOSIERUNGSFORMEN 有权基于聚醚和乙烯基单体作为粘合剂FOR固体含活性剂型共聚物的用途
公开(公告)号：EP2344138B1
公开(公告)日：2014-07-16
申请号：EP09783239.8
申请日：2009-09-21
申请人： BASF SE
CPC分类号： A61K47/34 , A61K9/1641 , A61K9/2031 , A61K9/2095
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5.发明公开VERWENDUNG VON COPOLYMEREN AUF BASIS VON POLYETHERN UND VINYLMONOMEREN ALS BINDEMITTEL FÜR FESTE WIRKSTOFFHALTIGE DOSIERUNGSFORMEN 有权基于聚醚和乙烯基单体作为粘合剂FOR固体含活性剂型共聚物的用途
公开(公告)号：EP2344138A2
公开(公告)日：2011-07-20
申请号：EP09783239.8
申请日：2009-09-21
申请人： BASF SE
CPC分类号： A61K47/34 , A61K9/1641 , A61K9/2031 , A61K9/2095
摘要： Use of water-soluble or water-dispersible copolymers obtained through radically-initiated polymerization of a mixture of i) 30 to 80 wt.-% of N-vinyl lactam, ii) 10 to 50 wt.-% of vinyl acetate and iii) 10 to 50 wt.-% of a polyether as a binder for the manufacture of dosing forms comprising solid active ingredients, said copolymers being conditioned in that the total of i), ii) and iii) is equal to 100 wt.-%.
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6.发明授权PHARMAZEUTISCHE FORMULIERUNG FÜR DIE HERSTELLUNG VON SCHNELL ZERFALLENDEN TABLETTEN 有权药物制剂FOR FAST崩解片剂的制造
公开(公告)号：EP2170273B1
公开(公告)日：2014-11-26
申请号：EP08760352.8
申请日：2008-06-02
申请人： BASF SE
CPC分类号： A61K9/0056 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/2018 , A61K9/2027 , A61K9/2054
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7.发明公开
公开(公告)号：EP2643363A1
公开(公告)日：2013-10-02
申请号：EP11843266.5
申请日：2011-11-21
申请人： BASF SE
CPC分类号： C08F126/06
摘要： Disclosed is a process for the preparation of low-peroxide crosslinked vinyllactam polymer by free-radical polymerization in the presence of at least one organic substance acting as antioxidant. The vinyllactam polymer is water-insolubly crosslinked polyvinylpyrrolidone or vinylpyrrolidone copolymer with vinylimidazole, vinylcaprolactam and/or vinyl acetate. The obtained vinyllactam polymer has low peroxide contents, and the peroxide contents do not increase or increase slightly within a certain time and low residual monomer contents. The obtained vinyllactam polymer is suitable to use in the field of pharmaceutical and food applications.
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公开(公告)号：EP2349218B1
公开(公告)日：2013-09-18
申请号：EP09783669.6
申请日：2009-10-02
申请人： BASF SE
发明人： KOLTER, Karl , MASCHKE, Angelika
CPC分类号： A61K9/1694 , A61K9/1635 , A61K9/2027
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公开(公告)号：EP2164461B1
公开(公告)日：2013-01-23
申请号：EP08760353.6
申请日：2008-06-02
申请人： BASF SE
CPC分类号： A61K9/0056 , A61K9/2018 , A61K9/2027
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10.发明授权SCHNELLDISPERGIERBARES, TEILCHENFÖRMIGES FILMÜBERZUGSMITTEL BASIEREND AUF POLYVINYLALKOHOL-POLYETHER-PFROPFCOPOLYMEREN 有权SCHNELLDISPERGIERBARES微粒薄膜包衣剂基于聚乙烯醇 - 聚醚接枝共聚物
公开(公告)号：EP2114375B1
公开(公告)日：2011-11-30
申请号：EP07857369.8
申请日：2007-12-11
申请人： BASF SE
CPC分类号： A61K9/284
摘要： The invention relates to solid particulate film coating agents consisting of: a) 40 - 90 % by weight, preferably 40 - 70 % by weight polyvinyl alcohol-polyether graft copolymers (component A), b) up to 60 % by weight, preferably between 20 and 45 % by weight of a coloured or achromatic colouring agent (component B), c) between 0 and 30 % by weight additional conventional auxiliary agents (component C). According to the invention, the quantities of components A to C total 100 % by weight. Said coating agents are obtained by the extrusion of a plastic mass of components A) to C) and by a subsequent shaping process.
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