公开(公告)号：EP1003609B1

公开(公告)日：2006-12-06

申请号：EP98934139.1

申请日：1998-06-22

申请人： BAXTER INTERNATIONAL INC. (a Delaware corporation)

发明人： MIN, Kyungyoon ,  BROWN, Richard, I. ,  BISCHOF, Daniel, F. ,  CORK, William, H. ,  CANTU, Robert, J.

IPC分类号： B04B11/04 ,  B01D21/26 ,  B04B5/04 ,  B04B13/00

CPC分类号： B01D21/302 ,  A61M1/3696 ,  B01D21/262 ,  B01D2221/10 ,  B04B5/0442 ,  B04B13/00 ,  B04B2005/045

摘要： A blood separation system operates in a first mode to convey whole blood into the inlet region (48) of a blood processing chamber (38) for centrifugal separation into packed red blood cells, a plasma constituent, and an interface, which carries mononuclear cells, between the packed red blood cells and the plasma constituent. The system removes packed red blood cells and the plasma constituent from the chamber (38), while maintaining the interface within the chamber (38). The system operates in a second mode to remove the interface from the chamber (38) by conveying packed red blood cells into the inlet region (48). An outlet path (46) conveys the removed interface from the chamber (38). The outlet path (46) includes a first sensing element (OS) to locate mononuclear cells in the removed interface and provide a sensed output upon locating mononuclear cells.

公开(公告)号：EP1706209A1

公开(公告)日：2006-10-04

申请号：EP04814506.4

申请日：2004-12-16

申请人： BAXTER INTERNATIONAL INC. (a Delaware corporation)

发明人： MIN, Kyungyoon ,  AKONUR, Alp ,  BROWN, Richard

IPC分类号： B04B5/04 ,  A61M1/36

CPC分类号： A61M1/3693 ,  A61M1/3696 ,  A61M1/38 ,  A61M2205/128 ,  B04B5/0442 ,  B04B2005/045

摘要： A separation apparatus and method are employed using a spearation channel (210) for rotation abut an axis. Such channel includes radially spaced apart inner (206) and outer (208) side wall portions and an end wall portion (224). An inlet (226) conveys fluid into the channel. A barrier (232) is located in the channel intermediate of the inner and outer side wall portions. A first flow path communicates between upstream and downstream sides of the barrier. A collection region may be located downstream of the barrier for communication with teh first flow path. An outer side wall section of the channel may be positioned radially outward of an upstream section thereof. The barrier (232) may joing the outer side wall portion (208) along a substantial portion of an axial length of the channel. First and second exit flow paths may allow communication with the channel either upstream or downstream of the barrier or both.

公开(公告)号：EP1003609A1

公开(公告)日：2000-05-31

申请号：EP98934139.1

申请日：1998-06-22

申请人： BAXTER INTERNATIONAL INC.(a Delaware corporation)

发明人： MIN, Kyungyoon ,  BROWN, Richard, I. ,  BISCHOF, Daniel, F. ,  CORK, William, H. ,  CANTU, Robert, J.

IPC分类号： B04B11/04 ,  B01D21/26

CPC分类号： B01D21/302 ,  A61M1/3696 ,  B01D21/262 ,  B01D2221/10 ,  B04B5/0442 ,  B04B13/00 ,  B04B2005/045

摘要： A blood separation system operates in a first mode to convey whole blood into the inlet region (48) of a blood processing chamber (38) for centrifugal separation into packed red blood cells, a plasma constituent, and an interface, which carries mononuclear cells, between the packed red blood cells and the plasma constituent. The system removes packed red blood cells and the plasma constituent from the chamber (38), while maintaining the interface within the chamber (38). The system operates in a second mode to remove the interface from the chamber (38) by conveying packed red blood cells into the inlet region (48). An outlet path (46) conveys the removed interface from the chamber (38). The outlet path (46) includes a first sensing element (OS) to locate mononuclear cells in the removed interface and provide a sensed output upon locating mononuclear cells.