公开(公告)号：EP0288205A2

公开(公告)日：1988-10-26

申请号：EP88303335.9

申请日：1988-04-13

申请人： BEECHAM GROUP PLC

发明人： Baker, Geoffrey Harold Beecham Pharmaceuticals ,  Dorgan, Roderick John Beecham Pharmaceuticals ,  Banks, Rhona Mary Beecham Pharmaceuticals ,  Poulton, Mark Edward Beecham Pharmaceuticals

IPC分类号： C07D493/22 ,  A01N43/90 ,  A61K31/35

CPC分类号： C07H19/01 ,  A01N43/90

摘要： Compounds of formula (VIII):
wherein R¹⁰ is hydroxy or methoxy and R¹¹ and R¹² are the same or different and each is selected from optionally protected hydroxy, alkoxy, acyloxy, sulphonyloxy, oxo and optionally O-substituted oximino, but excluding VM44864 and VM44866 as herein defined, are new and useful as anthelmintic agents.

摘要翻译： 式（VIII）化合物：其中R 1为羟基或甲氧基且R 1和R 2为相同或不同的化合物，其各自为任选保护的 羟基，烷氧基，酰氧基，磺酰氧基，氧代和任选的O-取代的肟基，但除了如本文所定义的VM44864和VM44866，是新的和有用的作为驱肠剂。

公开(公告)号：EP0288205A3

公开(公告)日：1989-10-25

申请号：EP88303335.9

申请日：1988-04-13

申请人： BEECHAM GROUP PLC

发明人： Baker, Geoffrey Harold Beecham Pharmaceuticals ,  Dorgan, Roderick John Beecham Pharmaceuticals ,  Banks, Rhona Mary Beecham Pharmaceuticals ,  Poulton, Mark Edward Beecham Pharmaceuticals

IPC分类号： C07D493/22 ,  A01N43/90 ,  A61K31/35

CPC分类号： C07H19/01 ,  A01N43/90

摘要： Compounds of formula (VIII):
wherein R¹⁰ is hydroxy or methoxy and R¹¹ and R¹² are the same or different and each is selected from optionally protected hydroxy, alkoxy, acyloxy, sulphonyloxy, oxo and optionally O-substituted oximino, but excluding VM44864 and VM44866 as herein defined, are new and useful as anthelmintic agents.

公开(公告)号：EP0353959A2

公开(公告)日：1990-02-07

申请号：EP89307693.5

申请日：1989-07-28

申请人： BEECHAM GROUP PLC

发明人： Baker, Geoffrey Harold Beecham Pharmaceuticals ,  Dorgan, Roderick John Beecham Pharmaceuticals ,  Morgan, David Owen Beecham Pharmaceuticals ,  Banks, Rhona Mary Beecham Pharmaceuticals ,  Blanchflower, Simon Edward Beecham Pharmaceuticals ,  Shelley, Peter Robin

IPC分类号： C07H19/01 ,  C07D493/22 ,  A61K31/70 ,  A61K31/365 ,  A01N43/90

CPC分类号： C07H19/01 ,  A01N43/90 ,  C12P17/181

摘要： There are disclosed novel compounds of formula (I)
wherein R¹ is hydrogen or optionally protected hydroxy; R² is alkoxy, optionally protected hydroxy, oxo or optionally O-substituted oximino; R³ is hydrogen, optionally protected hydroxy,or a group 4′-(α- L -oleandrosyl)-α- L -oleandrosyloxy or α - L -­oleandrosyloxy wherein the terminal hydroxy group is optionally protected; the dashed line represents an optional double bond; and R⁴, R⁵, R⁶ and R⁷ are the same or different and each is hydrogen or an organic radical; as well as a process for their production and their use as endectocides and pesticides.

摘要翻译： 公开了式（I）的新化合物，其中R 1是氢或任选保护的羟基; R 2是烷氧基，任选保护的羟基，氧代或任选的O-取代的肟基; R 3为氢，任选被保护的羟基，或4min-（α-L-肉豆蔻酰基）-α--L-烯丙基氧基或α-L-甘氨酰氧基的基团，其中末端羟基任选被保护; 虚线表示可选的双键; 和R 4，R 5，R 6和R 7相同或不同，各自为氢或有机基团; 以及其生产和使用作为结核苷脂和杀虫剂的过程。