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公开(公告)号：EP2725125A1
公开(公告)日：2014-04-30
申请号：EP12789707.2
申请日：2012-05-22
发明人： LUO, Huijuan , JI, Guanyu , JIANG, Hui , WU, Mingzhi , SUN, Jihua , WU, Renhua , WANG, Junwen , GAO, Fei
CPC分类号： C12Q1/6874 , C12N15/1065 , C12Q1/6806 , C12Q1/6869 , C40B50/06 , C12Q2523/125 , C12Q2525/191 , C12Q2535/122 , C12Q2537/159
摘要： Provided is a high throughput methylation detection method, particularly a combined sequence capture and bisulfite sequencing method. The method accurately and effectively analyzes the methylation status of the target area in several samples simultaneously, lowers the difficulty of probe design, enhances operation and application feasibility, and enables high throughput methylation detection of high accuracy on interested target sequences and areas in a complete genome. The method is targeted and conserves energy and time.
摘要翻译： 提供了高通量甲基化检测方法，特别是组合的序列捕获和亚硫酸氢盐测序方法。 该方法同时精确有效地分析了几个样本中目标区域的甲基化状态，降低了探针设计的难度，增强了操作和应用的可行性，并且在完整的基因组中使目标序列和区域的高准确度高通量甲基化检测 。 该方法是针对性的，节约能源和时间。
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公开(公告)号：EP2725125B1
公开(公告)日：2018-01-17
申请号：EP12789707.2
申请日：2012-05-22
发明人： LUO, Huijuan , JI, Guanyu , JIANG, Hui , WU, Mingzhi , SUN, Jihua , WU, Renhua , WANG, Junwen , GAO, Fei
CPC分类号： C12Q1/6874 , C12N15/1065 , C12Q1/6806 , C12Q1/6869 , C40B50/06 , C12Q2523/125 , C12Q2525/191 , C12Q2535/122 , C12Q2537/159
摘要： Provided is a high throughput methylation detection method, particularly a combined sequence capture and bisulfite sequencing method. The method accurately and effectively analyzes the methylation status of the target area in several samples simultaneously, lowers the difficulty of probe design, enhances operation and application feasibility, and enables high throughput methylation detection of high accuracy on interested target sequences and areas in a complete genome. The method is targeted and conserves energy and time.
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