公开(公告)号：EP1290052B1

公开(公告)日：2006-05-03

申请号：EP01940627.1

申请日：2001-05-29

申请人： BIO MERIEUX

发明人： CHARREYRE, Marie-Thérèse ,  D'AGOSTO, Franck ,  FAVIER, Arnaud ,  PICHOT, Christian ,  MANDRAND, Bernard

IPC分类号： C08F293/00 ,  C08L53/00 ,  G01N33/545

CPC分类号： C08L53/00 ,  C08F293/005

摘要： The invention concerns a biocompatible polymer having a mole weight more than 50000 g/mole, preferably 90000 g/mole for fixing biological ligands comprising at least a first linear segment consisting of a hydrophobic homopolymer derived from polymerisation of a hydrophobic monomer A; a second linear segment consisting of a hydrophilic polymer derived from copolymerisation of a monomer B bearing a reactive function X and a hydrophilic monomer C not bearing any reactive function, said second segment being covalently bound to one end of the first segment. The invention also concerns a biological polymer-ligand-conjugate, a device for capturing a target molecule comprising a solid support whereon is immobilised a biological polymer-ligand conjugate and methods for preparing said polymer. The invention is mainly applicable in the field of diagnosis.

公开(公告)号：EP1290052A1

公开(公告)日：2003-03-12

申请号：EP01940627.1

申请日：2001-05-29

申请人： BIO MERIEUX

发明人： CHARREYRE, Marie-Thérèse ,  D'AGOSTO, Franck ,  FAVIER, Arnaud ,  PICHOT, Christian ,  MANDRAND, Bernard

IPC分类号： C08F293/00 ,  C08L53/00 ,  G01N33/545

CPC分类号： C08L53/00 ,  C08F293/005

摘要： The invention concerns a biocompatible polymer having a mole weight more than 50000 g/mole, preferably 90000 g/mole for fixing biological ligands comprising at least a first linear segment consisting of a hydrophobic homopolymer derived from polymerisation of a hydrophobic monomer A; a second linear segment consisting of a hydrophilic polymer derived from copolymerisation of a monomer B bearing a reactive function X and a hydrophilic monomer C not bearing any reactive function, said second segment being covalently bound to one end of the first segment. The invention also concerns a biological polymer-ligand-conjugate, a device for capturing a target molecule comprising a solid support whereon is immobilised a biological polymer-ligand conjugate and methods for preparing said polymer. The invention is mainly applicable in the field of diagnosis.