专利检索 ap:("BIO-RAD LABORATORIES, INC.") AND inv:"KRONMAL, Gregory, S." 第 1 页

1.

发明授权
POLYMORPHISMS AND NEW GENES IN THE REGION OF THE HUMAN HEMOCHROMATOSIS GENE 失效
标题翻译：多态性与新基因在人类HEMOCHROMATOSISGENS区域

公开(公告)号：EP0960114B1

公开(公告)日：2007-09-19

申请号：EP97910741.4

申请日：1997-09-30

申请人： BIO-RAD LABORATORIES, INC.

发明人： FEDER, John, N. , KRONMAL, Gregory, S. , LAUER, Peter, M. , RUDDY, David, A. , THOMAS, Winston, J. , TSUCHIHASHI, Zenta , WOLFF, Roger, K.

IPC分类号： C12Q1/68 , C07H21/04 , C12N15/63

CPC分类号： C07K14/70503 , C07K14/70539 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172

摘要： Polymorphic sites in the region surrounding the HFE gene are provided. These polymorphisms are useful as surrogate markers in diagnostic assays for hemochromatosis. Additionally, a fine structure map of the 1 megabase region surrounding the HFE gene is provided, along with 235 kb of DNA sequence and 8 loci corresponding to candidate genes within the 1 megabase region, and in the purification of related proteins.