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公开(公告)号:EP0701606A1
公开(公告)日:1996-03-20
申请号:EP94915405.0
申请日:1994-04-22
发明人: GARFINKEL, Leonard , GORECKI, Marian , PANET, Amos
CPC分类号: C07K14/755 , A61K38/37 , A61K38/49 , A61K31/60 , A61K2300/00
摘要: A method is provided for the use of a fragment of von Willebrand Factor (vWF) comprising the platelet glycoprotein Ib (GPIb) binding domain in conjunction with known therapies to obtain enhanced protection against thrombosis, improved thrombolysis, and a decreased likelihood of reocclusion following thrombolytic treatment. Additionally, a method is provided for the use of the vWF fragment and aspirin to prevent complications following traumatic vascular damage.