公开(公告)号：EP0896526A1

公开(公告)日：1999-02-17

申请号：EP97914235.0

申请日：1997-03-13

申请人： BIOCHEMIE GESELLSCHAFT M.B.H.

发明人： RANEBURGER, Johannes ,  ZEISL, Erich

IPC分类号： A61K9 ,  A61K31

CPC分类号： A61K31/545 ,  A61K9/1688 ,  A61K31/43 ,  Y10S514/951 ,  A61K2300/00

摘要： Auxiliary-free agglomerates of a β-lactam antibiotic; a mixture of agglomerates of an active β-lactam antibiotic and a second pharmaceutically active agent, with or without auxiliaries; a tablet comprising compressed agglomerates of a β-lactam antibiotic optionally in mixture with pharmaceutically acceptable auxiliaries; and a tablet comprising compressed agglomerates of a β-lactam antibiotic in mixture with a second pharmaceutically active agent and with or without pharmaceutically acceptable auxiliaries.

公开(公告)号：EP1133298A1

公开(公告)日：2001-09-19

申请号：EP99959327.0

申请日：1999-11-24

申请人： BIOCHEMIE Gesellschaft m.b.H.

发明人： JENNEWEIN, Herwig ,  RANEBURGER, Johannes

IPC分类号： A61K31/546 ,  A61K9/14 ,  A61K9/20 ,  A61K9/36 ,  A61P31/04

CPC分类号： A61K9/143 ,  A61K9/146 ,  A61K9/2009 ,  A61K9/2018 ,  A61K9/2027 ,  A61K9/2054 ,  A61K31/545

摘要： Cefuroxime axetil in a non-gelatinous form on contact with an aqueous liquid, e.g. in the form of a solid solution in a polymer or in the form of a solid dispersion on a carrier, e.g. useful for the production of pharmaceutical compositions comprising cefuroxime axetil as an active ingredient and the use of cefuroxime axetil in the manufacture of an oral dosage form which does not exhibit an adverse food effect.

公开(公告)号：EP1328528A1

公开(公告)日：2003-07-23

申请号：EP01987751.3

申请日：2001-10-18

申请人： BIOCHEMIE Gesellschaft m.b.H.

发明人： HORKOVICS-KOVATS, Stefan ,  RANEBURGER, Johannes ,  SCHWARZ, Franz, Xaver

IPC分类号： C07D503/02 ,  C07D503/08 ,  C12P17/18 ,  A61K31/43

CPC分类号： C07D503/00

摘要： Clavulanic acid, in which the median of the particles is from 8 νm to 35 νm and their use in pharmaceutical compositions.