公开(公告)号：EP1608308A4

公开(公告)日：2009-08-26

申请号：EP04707051

申请日：2004-01-30

申请人： BIOGAIA AB ,  BAYLOR COLLEGE MEDICINE

发明人： VERSALOVIC JAMES ,  PENA JEREMY A ,  CONNOLY EAMONN

IPC分类号： C12N1/12 ,  A61K20060101 ,  A61K6/00 ,  A61K35/00 ,  A61K35/74 ,  A61K38/17 ,  C07K14/335 ,  C12N1/20 ,  C12R1/225

CPC分类号： C12N1/20 ,  A61K35/744 ,  A61K35/747 ,  A61K38/13 ,  A61K45/06 ,  C07K14/335 ,  C12R1/225 ,  A61K2300/00

摘要： In the present invention, lactic acid bacteria produce soluble factors (such as peptides or proteins) that block inflammatory responses in a mechanism that depends on G proteins and is post-transcriptional to effectively block protein production or secretion by cells.