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公开(公告)号:EP1044047A4
公开(公告)日:2008-04-16
申请号:EP98957835
申请日:1998-11-12
申请人: BIOTAGE INC
发明人: GREEN JEFFREY R , KASTER JEFFREY A , LANCASTER VICTOR R , LEAVESLEY PETER J , MCNEIL GARY L , RANSOHOFF THOMAS C , VAN DAVELAAR PETER C
CPC分类号: G01N30/6091 , B01D15/20 , B01D15/22 , G01N30/60 , G01N30/6004 , G01N30/6017 , G01N30/6047 , G01N2030/522 , G01N2030/8881
摘要: A chromatography cartridge assembly includes a cartridge and first (40) and second end caps (42). A wall of the cartridge (22) defines a chamber (82) for containing chromatography media. The end caps define inlet (62) and outlet passages (66), respectively, for flow of process fluid. The first end cap defines flow distributor passages (100) for distributing process fluid across a cross-sectional area of the chamber, and the second end cap defines flow collector passages (104) for collecting process fluid from across a cross-sectional area of the chamber. A clamp is circumferentially located about the cartridge wall for applying a radial load through the wall to the first end cap to fix the first end cap in a desired position.
摘要翻译: 色谱柱组件包括盒和第一和第二端盖。 筒的壁限定用于容纳色谱介质的室。 端盖分别限定用于工艺流体流动的入口和出口通道。 第一端盖限定了用于在室的横截面区域上分配工艺流体的流量分配器通道,并且第二端盖限定了用于从室的横截面积收集工艺流体的流动收集器通道。 围绕盒壁周向地设置夹具,用于将径向载荷穿过壁施加到第一端盖,以将第一端盖固定在期望的位置。