公开(公告)号：EP3158084A4

公开(公告)日：2017-11-29

申请号：EP15809356

申请日：2015-06-19

申请人： BIOVENTURES LLC

发明人： KIAEI MAHMOUD

IPC分类号： C12Q1/68 ,  A01K67/027 ,  C12N15/85

CPC分类号： C07K14/4716 ,  A01K67/0275 ,  A01K67/0278 ,  A01K2207/15 ,  A01K2217/052 ,  A01K2217/072 ,  A01K2217/206 ,  A01K2227/105 ,  A01K2267/0318 ,  A61K49/0008 ,  C12N15/8509

摘要： The present disclosure provides genetically modified animals and cells comprising a polynucleotide encoding human profilin1. Also provided are methods of assessing the effects of agents in genetically modified animals and cells comprising a polynucleotide encoding human profilin1.