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    METHOD FOR DETERMINING AMINO-TERMINAL PROANP IN PATIENTS HAVING A CARDIAC DISEASE OR BEING SUSPECTED OF DEVELOPING OR HAVING A CARDIAC DISEASE
    3.
    发明公开
    METHOD FOR DETERMINING AMINO-TERMINAL PROANP IN PATIENTS HAVING A CARDIAC DISEASE OR BEING SUSPECTED OF DEVELOPING OR HAVING A CARDIAC DISEASE 有权
    氨基末端proANP的IN与心脏疾病的患者的方法Bestimung中间部分或怀疑一个演变OR 本心脏病

    公开(公告)号：EP2145191A1

    公开(公告)日：2010-01-20

    申请号：EP08750087.2

    申请日：2008-05-06

    申请人： BRAHMS Aktiengesellschaft

    发明人： BERGMANN, Andreas ,  PAPASSOTIRIOU, Jana ,  STRUCK, Joachim ,  MORGENTHALER, Nils ,  ANKER, Stefan

    IPC分类号： G01N33/74

    CPC分类号： G01N33/74 ,  G01N2333/58 ,  G01N2800/324

    摘要： The present invention relates to an in vitro method for medical diagnosis, prognosis and therapy follow-up for patients having a cardiac disease or being suspected of developing or having a cardiac disease comprising the steps of: providing a sample of a patient having a cardiac disease or being suspected of developing or having a cardiac disease, determining amino-terminal proANP or partial peptides thereof having from 12 to 98 amino acids in said sample using at least one antibody that binds specifically to a partial sequence of amino- terminal proANP, attributing the determined amino-terminal proANP level or the level of partial peptides thereof to a clinical picture wherein the attribution is carried out independent of the BMI of the patient. The present invention further concerns a rapid test assay and a kit for conducting the method of the present invention and the use of antibodies suitable for the method and assays according to the present invention.