专利检索 ap:("BROOKHAVEN SCIENCE ASS LLC") AND inv:"SLATKIN DANIEL N" 第 1 页

1.

发明公开
NOVEL METALLOPORPHYRINS AND THEIR USES AS RADIOSENSITIZERS FOR RADIATION THERAPY 有权
标题翻译：新的金属卟啉及其作为放射治疗放射增敏剂使用

公开(公告)号：EP1404319A4

公开(公告)日：2005-03-23

申请号：EP02737384

申请日：2002-06-05

申请人： BROOKHAVEN SCIENCE ASS LLC

发明人： MIURA MICHIKO , SLATKIN DANIEL N

IPC分类号： A61N5/10 , A61K31/409 , A61K31/69 , A61K41/00 , A61K51/00 , A61K51/04 , A61P35/00 , C07D487/22 , C07F5/02

CPC分类号： A61K51/0485 , A61K31/409 , A61K41/0038 , A61K41/0095 , C07D487/22

摘要： The present invention covers radiosensitizers containing as an active ingredient halogenated derivatives of boronated porphyrins containing multiple carborane cages which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron-capture therapy and photodynamic therapy. The present invention also covers methods for using these radiosensitizers in tumor imaging and cancer treatment.