公开(公告)号：EP1648424A2

公开(公告)日：2006-04-26

申请号：EP04755975.2

申请日：2004-06-23

申请人： Banner Pharmacaps, Inc.

发明人： ARCHIBALD, Don, A. ,  FANG, Qi ,  FONKWE, Linus, G. ,  DIETEL, Gregory, L. ,  CASAULT, Charles, S.

IPC分类号： A61K9/48 ,  A61J3/07 ,  B29C47/00

CPC分类号： A61K9/4891 ,  A61K9/4816

摘要： A film-forming composition comprising a hydrocolloid, a plasticizer, and water is described. A process and apparatus for producing a non-gelatin film comprising a hydrocolloid, a plasticizer, and water is also disclosed. The process includes combining at least one non-gelatin hydrocolloid, water, and at least one plasticizer into a substantially homogeneous film-forming composition comprising at least about 40 percent water by weight. A substantial portion of the water is then extracted from the film-forming composition to form a dried portion having a water content of less than or equal to about 25 percent by weight. The dried portion of the film-forming composition is formed into a film. A film produced according to the process preferably has a tensile strength at rupture of at least about 5 N, and a percent elongation of at least about 50 percent at rupture at room temperature. An apparatus for performing the process is also described, as well oral dosage forms encapsulated or enrobed in the produced film.