专利检索 ap:("Baxalta Incorporated" OR "Baxalta GmbH") AND inv:"BRUCKSCHWAIGER, Leopold" 第 1 页

1.

发明授权
STABLE CO-FORMULATION OF HYALURONIDASE AND IMMUNOGLOBULIN, AND METHODS OF USE THEREOF 有权
标题翻译：稳定共表达透明质酸酶及免疫球蛋白的制造方法及其使用

公开(公告)号：EP2477603B1

公开(公告)日：2016-03-30

申请号：EP10760140.3

申请日：2010-09-16

申请人： Baxalta Incorporated , Baxalta GmbH

发明人： TESCHNER, Wolfgang , SVATOS, Sonja , BRUCKSCHWAIGER, Leopold , WEBER, Alfred , SCHWARZ, Hans-Peter , LEI, Laura

IPC分类号： A61K9/00 , A61K47/36 , A61K47/42 , A61K39/00 , A61K39/395 , C07K16/00 , C07K16/06 , C12N9/24

CPC分类号： A61K39/00 , A61K9/0021 , A61K39/39591 , A61K47/42 , A61K2039/505 , C07K16/00 , C07K16/06 , C07K2317/21 , C12N9/2474 , C12Y302/01035 , Y02A50/464

摘要： Provided herein are stable co-formulations of immunoglobulin and hyaluronidase that are stable to storage in liquid form at room temperature for at least 6 months and at standard refrigerator temperatures for 1-2 years. Such co-formulations can be used in methods of treating IG-treatable diseases or conditions by subcutaneous administration.