公开(公告)号：EP1406908A1

公开(公告)日：2004-04-14

申请号：EP02745409.9

申请日：2002-06-25

申请人： Bayer HealthCare AG

发明人： FEURER, Achim ,  FLUBACHER, Dietmar ,  WEIGAND, Stefan ,  STASCH, Johannes-Peter ,  STAHL, ELke ,  SCHENKE, Thomas ,  ALONSO-ALIJA, Cristina ,  WUNDER, Frank ,  LANG, Dieter ,  DEMBOWSKY, Klaus ,  STRAUB, Alexander ,  PERZBORN, Elisabeth

IPC分类号： C07D519/00 ,  C07D471/04 ,  C07D498/08 ,  A61K31/5386 ,  A61P7/02 ,  A61P9/10

CPC分类号： C07D471/04

摘要： The invention relates to novel pyrazolopyridine derivatives of formula (I), wherein R1 represents (a) or (b) and n represents 1 or 2 and R2 represents H NH¿2?. The invention also relates to salts, isomers and hydrates thereof as stimulators for soluble guanylate cyclase and to their use as agents in the treatment of cardiovascular diseases, hypertonicity, thrombo-embolic diseases and ischemia, sexual dysfunction or inflammations and for the treatment of diseases of the central nervous system.