公开(公告)号：EP2563762B1

公开(公告)日：2015-07-22

申请号：EP11717250.2

申请日：2011-04-26

申请人： Bayer Intellectual Property GmbH

发明人： KRÜGER, Joachim ,  GROSSBACH, Danja ,  PAULSEN, Holger ,  KROH, Walter

IPC分类号： C07D213/64

CPC分类号： C07D213/64

公开(公告)号：EP2563762A1

公开(公告)日：2013-03-06

申请号：EP11717250.2

申请日：2011-04-26

申请人： Bayer Intellectual Property GmbH

发明人： KRÜGER, Joachim ,  GROSSBACH, Danja ,  PAULSEN, Holger ,  KROH, Walter

IPC分类号： C07D213/64

CPC分类号： C07D213/64

摘要： The invention relates to a method for producing substituted 3-(2- hydroxyethyl)-1-[4-nitrophenyl]pyridin-2(1H)-ones used as important intermediate compounds for producing medicaments.

公开(公告)号：EP2576547A1

公开(公告)日：2013-04-10

申请号：EP11720806.6

申请日：2011-05-24

申请人： Bayer Intellectual Property GmbH

发明人： FOLLMANN, Markus ,  STASCH, Johannes-Peter ,  REDLICH, Gorden ,  ACKERSTAFF, Jens ,  GRIEBENOW, Nils ,  KROH, Walter ,  KNORR, Andreas ,  BECKER, Eva-Maria ,  WUNDER, Frank ,  LI, Volkhart Min-Jian ,  HARTMANN, Elke ,  MITTENDORF, Joachim ,  SCHLEMMER, Karl-Heinz ,  JAUTELAT, Rolf ,  BIERER, Donald

IPC分类号： C07D471/04 ,  A61K31/437 ,  A61P9/00 ,  A61P15/00

CPC分类号： A61K31/506 ,  A61K45/06 ,  C07C57/145 ,  C07C309/04 ,  C07C309/05 ,  C07D471/04

摘要： The present application relates to novel substituted 5-fluoro-lH-pyrazolopyridines, to processes for preparation thereof, to the use thereof alone or in combination for treatment and/or prophylaxis of disorders, and to the use thereof for production of medicaments for treatment and/or prophylaxis of disorders, especially for treatment and/or prophylaxis of cardiovascular disorders.

公开(公告)号：EP2590979A1

公开(公告)日：2013-05-15

申请号：EP11732409.5

申请日：2011-07-05

申请人： Bayer Intellectual Property GmbH

发明人： FOLLMANN, Markus ,  STASCH, Johannes-Peter ,  REDLICH, Gorden ,  ACKERSTAFF, Jens ,  GRIEBENOW, Nils ,  KNORR, Andreas ,  WUNDER, Frank ,  LI, Volkhart, Min-Jian ,  KROH, Walter ,  BÄRFACKER, Lars

IPC分类号： C07D487/04 ,  A61K31/519 ,  A61K31/522 ,  A61P9/00

CPC分类号： C07D471/04 ,  A61K31/519 ,  A61K31/527 ,  A61K31/53 ,  A61K45/06 ,  C07D487/04 ,  C07D491/107

摘要： The invention relates to novel ring-fused pyrimidines and triazines, to methods for the production thereof, use thereof on its own or combined for the treatment and/or prophylaxis of diseases and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular diseases.