公开(公告)号：EP2285443A2

公开(公告)日：2011-02-23

申请号：EP09739927.3

申请日：2009-05-01

申请人： Bayer Schering Pharma AG

发明人： EWING, Benjamin, T. ,  BRUCKER, Gregory, G. ,  BEDNAR, Scott, A. ,  PERIARD, John, R. ,  SHARMA, Ashok, K. ,  SAVAGE, Steven, D. ,  UBER, Arthur, E., III ,  DICKERSON, Brian, P.

IPC分类号： A61M25/10

CPC分类号： A61M25/104 ,  A61B17/22 ,  A61B2017/22001 ,  A61B2017/22051 ,  A61B2017/22061 ,  A61L29/08 ,  A61L29/16 ,  A61L2420/02 ,  A61M25/1002 ,  A61M25/1029 ,  A61M25/1038 ,  A61M2025/1004 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2025/1075 ,  A61M2210/12 ,  Y10T29/49826

摘要： Various methods for optimizing coating of medical devices, such as balloon catheters are disclosed. One method configures catheter balloon folds based on balloon diameter and volume. Other methods include using a specifically-sized protective sheath, using a vacuum, using pressure, pulling the balloon through a coating solution, using at least one spacer or a wick between at least one fold for metering a therapeutic coating into the folds of the balloon, placing an intermediate layer between the balloon and the therapeutic coating, placing a soluble film having a therapeutic agent around the catheter balloon or inside the folds, and any combination thereof. Balloon catheters and catheter balloons having a specific folding configuration, a specifically-sized protective sheath, an intermediate layer, or a soluble film are also disclosed.