公开(公告)号：EP2005166B1

公开(公告)日：2011-06-01

申请号：EP07753313.1

申请日：2007-03-16

申请人： BioMarin Pharmaceutical Inc.

发明人： WHITE, Joleen ,  FLAY, Lisa, Argento ,  FOEHR, Erik ,  TANIGUCHI, Gary ,  PRINCE, William, S. ,  ZHAO, Bin

IPC分类号： G01N33/50

CPC分类号： G01N33/6854 ,  G01N33/573 ,  G01N2333/924

摘要： The present invention relates to methods for screening body fluids or tissues for antibodies, including neutralizing and isotype-specific antibodies, against lysosomal enzymes administered as part of enzyme replacement therapy.

公开(公告)号：EP2005166A2

公开(公告)日：2008-12-24

申请号：EP07753313.1

申请日：2007-03-16

申请人： BioMarin Pharmaceutical Inc.

发明人： WHITE, Joleen ,  FLAY, Lisa, Argento ,  FOEHR, Erik ,  TANIGUCHI, Gary ,  PRINCE, William, S. ,  ZHAO, Bin

IPC分类号： G01N33/50

CPC分类号： G01N33/6854 ,  G01N33/573 ,  G01N2333/924

摘要： The present invention relates to methods for screening body fluids or tissues for antibodies, including neutralizing and isotype-specific antibodies, against lysosomal enzymes administered as part of enzyme replacement therapy.