公开(公告)号：EP4287191A2

公开(公告)日：2023-12-06

申请号：EP23200173.5

申请日：2018-02-12

申请人： BioNTech US Inc.

发明人： ABELIN, Jennifer, Grace ,  OSLUND, Rob, Carl ,  HACOHEN, Nir ,  BARTHELME, Dominik ,  ROONEY, Michael

IPC分类号： G16B35/20

摘要： The present disclosure provides compositions and methods for isolating HLA-peptides from cells. The present disclosure provides a universal platform and methods for profiling the HLA-peptidome, enabling identification of endogenously presented HLA-peptides from cell lines expressing any possible class I or II construct.

公开(公告)号：EP4287191A3

公开(公告)日：2024-03-06

申请号：EP23200173.5

申请日：2018-02-12

申请人： BioNTech US Inc.

发明人： ABELIN, Jennifer, Grace ,  OSLUND, Rob, Carl ,  HACOHEN, Nir ,  BARTHELME, Dominik ,  ROONEY, Michael

IPC分类号： G01N33/50 ,  C12Q1/6886 ,  G01N33/68 ,  G01N33/574 ,  C40B40/02 ,  A61K39/39 ,  G16B35/20 ,  A61K39/00 ,  C40B30/04

摘要： The present disclosure provides compositions and methods for isolating HLA-peptides from cells. The present disclosure provides a universal platform and methods for profiling the HLA-peptidome, enabling identification of endogenously presented HLA-peptides from cell lines expressing any possible class I or II construct.