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    NOVEL USE OF LIGNAN-TYPE COMPOUNDS OR EXTRACT OF NUTMEG OR ARIL OF NUTMEG COMPRISING THE SAME
    2.
    发明公开
    NOVEL USE OF LIGNAN-TYPE COMPOUNDS OR EXTRACT OF NUTMEG OR ARIL OF NUTMEG COMPRISING THE SAME 有权
    NEUE VERWENDUNG VON AUS MUSKATEXTRAKT ODER MUSKATARILLUS EXTRAKT ISOLIERTEN LIGNANVERBINDUNGEN

    公开(公告)号：EP2200576A2

    公开(公告)日：2010-06-30

    申请号：EP08839723.7

    申请日：2008-10-17

    申请人： Biocare Co., Ltd. ,  NEWTREE CO., LTD.

    发明人： HWANG, Jae-Kwan ,  CHO, Yu-Mi ,  KIM, Gyu Hoi ,  KIM, Jeong Hwan ,  LEE, Hae Ji ,  OH, Hyun In ,  CHUNG, Hee Chul ,  CHUNG, Jae Youn ,  KIM, Do Un

    IPC分类号： A61K8/49

    CPC分类号： A61Q19/02 ,  A61K8/4973 ,  A61K8/97 ,  A61K31/357 ,  A61K36/185

    摘要： The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening.

    摘要翻译： 本发明涉及木质素型化合物或含有该木素素类化合物的肉豆蔻或肉豆蔻酸的提取物的新用途。 更具体地，本发明涉及一种皮肤美白组合物，其包含木素素型化合物或包含该组合物的肉豆蔻或肉豆蔻的提取物。 由于化学式1〜3所示的木酚素化合物或肉豆蔻肉豆蔻酸的提取物通过抑制黑色素生成和酪氨酸酶活性而具有优异的皮肤美白活性，因此可用于制备化妆品组合物，食品组合物或药物组合物 用于皮肤美白。

    USE OF LIGNAN COMPOUND FOR ANTI-WRINKLE TREATMENT
    4.
    发明公开
    USE OF LIGNAN COMPOUND FOR ANTI-WRINKLE TREATMENT 审中-公开
    使用木脂素连接对于治疗皱纹

    公开(公告)号：EP2170255A2

    公开(公告)日：2010-04-07

    申请号：EP08766506.3

    申请日：2008-06-20

    申请人： Biocare CO., LTD. ,  Hwang, Jae-Kwan

    发明人： HWANG, Jae-Kwan ,  LEE, Hae Ji ,  LEE, Jae Young ,  SHIM, Jae-Seok ,  KIM, Jeong Hwan

    IPC分类号： A61K8/34

    摘要： The present invention relates to a novel use of lignan compounds, which are isolated and purified from nutmeg or the aril of nutmeg for anti-wrinkle, and more particularly, the present invention relates to a novel use for anti-wrinkle of an extract of the nutmeg or an extract of the aril of the nutmeg, fragrin A, austobailignan 7, licarin E, and macelignan. The extracts and lignan compounds of the present invention have activities in suppressing collagen degradation enzyme-1 (MMP-I, matrix metalloprotei-nase-1) and formation of new collagen (type-1 procollagen), thereby having effect on inhibitng wrinkle caused by photoaging. Accordingly, the extracts and lignan compounds of the present invention may be useful for preventing or treating wrinkle caused by photoaging.