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公开(公告)号：EP2858500A2
公开(公告)日：2015-04-15
申请号：EP13800631.7
申请日：2013-06-07
发明人： HOPKINS, Brian, T. , CAI, Xiongwei , CHAN, Timothy R. , CONLON, Patrick , HUMORA, Michael , JENKINS, Tracy J. , MACPHEE, J. Michael , SHI, Xianglin , MILLER, Ross A. , THOMPSON, Andrew
IPC分类号： A01N43/40 , A61K31/435 , A61K31/445
CPC分类号： C07D401/14 , C07B2200/13 , C07D207/16 , C07D207/28 , C07D211/56 , C07D401/04
摘要： The present invention provides a compound, solid forms, and compositions thereof, which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same. The present invention also provides methods of making provided compound and solid forms.
摘要翻译： 本发明提供一种化合物，固体形式及其组合物，它们可用作布鲁顿氏酪氨酸激酶的抑制剂，并表现出所希望的特征。 本发明还提供了制备所提供的化合物和固体形式的方法。
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公开(公告)号：EP2858499A1
公开(公告)日：2015-04-15
申请号：EP13800042.7
申请日：2013-06-07
发明人： HOPKINS, Brian T. , CONLON, Patrick , CHAN, Timothy R. , JENKINS, Tracy J. , CAI, Xiongwei , HUMORA, Michael , SHI, Xianglin , MILLER, Ross A. , THOMPSON, Andrew
IPC分类号： A01N43/40 , A61K31/435 , A61K31/445
CPC分类号： C07D401/14
摘要： The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
摘要翻译： 本发明提供了可用作布鲁顿酪氨酸激酶抑制剂并表现出其所需特性的化合物及其组合物。
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公开(公告)号：EP3385263A1
公开(公告)日：2018-10-10
申请号：EP18171833.9
申请日：2013-06-07
发明人： HOPKINS, Brian T. , CONLON, Patrick , CHAN, Timothy R. , JENKINS, Tracy J. , CAI, Xiongwei , HUMORA, Michael , SHI, Xianglin , MILLER, Ross A. , THOMPSON, Andrew
IPC分类号： C07D401/14 , A61K31/435 , A61K31/445 , A61P37/00
摘要： The present invention provides pyrimidinyl compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号：EP3385263B1
公开(公告)日：2020-07-22
申请号：EP18171833.9
申请日：2013-06-07
发明人： HOPKINS, Brian T. , CONLON, Patrick , CHAN, Timothy R. , JENKINS, Tracy J. , CAI, Xiongwei , HUMORA, Michael , SHI, Xianglin , MILLER, Ross A. , THOMPSON, Andrew
IPC分类号： C07D401/14 , A61K31/435 , A61K31/445 , A61P37/00
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公开(公告)号：EP2858499B1
公开(公告)日：2018-05-16
申请号：EP13800042.7
申请日：2013-06-07
发明人： HOPKINS, Brian T. , CONLON, Patrick , CHAN, Timothy R. , JENKINS, Tracy J. , CAI, Xiongwei , HUMORA, Michael , SHI, Xianglin , MILLER, Ross A. , THOMPSON, Andrew
IPC分类号： C07D401/14 , A61K31/435 , A61K31/445 , A61P37/00
CPC分类号： C07D401/14
摘要： The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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