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公开(公告)号:EP3191519A1
公开(公告)日:2017-07-19
申请号:EP15767053.0
申请日:2015-09-11
申请人: Biogen MA Inc.
发明人: CAMERON, Thomas Owen , CRACKOWER, Michael Adam , DOLINSKI, Brian M. , HANF, Karl J. M. , MCCURLEY, Amy Theresa , PEDERSON, Nels Eric , PREYER, Martin , QIAN, Fang , VIOLETTE, Shelia M. , WEINREB, Paul Henry
IPC分类号: C07K16/28
CPC分类号: C07K16/2839 , C07K2317/24 , C07K2317/41 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: Humanized antibodies and antibody fragments that bind to αvβ5 are disclosed. Also disclosed are methods of using the disclosed antibodies and antibody fragments to treat or prevent αvβ5-mediated diseases.
摘要翻译: 公开了与αvβ5结合的人源化抗体和抗体片段。 还公开了使用所公开的抗体和抗体片段来治疗或预防αvβ5介导的疾病的方法。