公开(公告)号：EP3891146A1

公开(公告)日：2021-10-13

申请号：EP19828102.4

申请日：2019-12-04

申请人： Biogen MA Inc.

发明人： GENUNG, Nathan ,  GUCKIAN, Kevin, M. ,  VESSELS, Jeffrey ,  ZHANG, Lei ,  GIANATASSIO, Ryan ,  LIN, Edward Yin, Shiang ,  XIN, Zhili

IPC分类号： C07D417/14 ,  A61P25/28 ,  A61K31/5377 ,  A61K31/496 ,  A61K31/551 ,  A61K31/553

公开(公告)号：EP4327814A3

公开(公告)日：2024-04-24

申请号：EP23199729.7

申请日：2019-12-04

申请人： Biogen MA Inc.

发明人： GENUNG, Nathan ,  GUCKIAN, Kevin, M ,  VESSELS, Jeffrey ,  ZHANG, Lei ,  GIANATASSIO, Ryan ,  LIN, Edward Yin, Shiang ,  XIN, Zhili

IPC分类号： C07D417/14 ,  A61P25/28 ,  A61K31/551 ,  A61K31/553

CPC分类号： C07D417/14 ,  A61P25/28

摘要： Described herein are compounds represented by formula (I)

or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of preparing and using the same. The variables Ar, X, R1, R3, R4, Y1, Y2, m, n, and p are as defined herein.

公开(公告)号：EP4327814A2

公开(公告)日：2024-02-28

申请号：EP23199729.7

申请日：2019-12-04

申请人： Biogen MA Inc.

发明人： GENUNG, Nathan ,  GUCKIAN, Kevin, M ,  VESSELS, Jeffrey ,  ZHANG, Lei ,  GIANATASSIO, Ryan ,  LIN, Edward Yin, Shiang ,  XIN, Zhili

IPC分类号： A61K31/553

摘要： Described herein are compounds represented by formula (I)

or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of preparing and using the same. The variables Ar, X, R 1 , R 3 , R 4 , Y 1 , Y 2 , m, n, and p are as defined herein.