公开(公告)号：EP1841735A1

公开(公告)日：2007-10-10

申请号：EP05823663.9

申请日：2005-12-22

申请人： Biolipox AB

发明人： PELCMAN, Benjamin ,  OLOFSSON, Kristofer ,  KATKEVICS, M. Latvian Inst. of Organic Synthesis ,  OZOLA, Vita Latvian Institute of Organic Synthesis ,  SUNA, Edgars Latvian Inst. of Organic Synthesis ,  KALVINS, Ivars Latvian Inst. of Organic Synthesis ,  TRAPENCIERIS, P Latvian Inst. of Organic Synthesis ,  KATKEVICA, Dace Latvian Inst. of Organic Synthesis ,  SCHAAL, Wesley

IPC分类号： C07D209/42 ,  A61P11/00 ,  A61P29/00 ,  A61K31/404 ,  C07D401/04 ,  C07D403/04 ,  C07D405/04 ,  C07D401/12

CPC分类号： C07D401/04 ,  C07D209/42 ,  C07D401/12 ,  C07D403/04 ,  C07D405/04

摘要： There is provided compounds of formula (I), wherein X1, Q, T, Y, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

公开(公告)号：EP1841735B1

公开(公告)日：2011-03-09

申请号：EP05823663.9

申请日：2005-12-22

申请人： Biolipox AB

发明人： PELCMAN, Benjamin ,  OLOFSSON, Kristofer ,  KATKEVICS, Martins Latvian Inst. of Organic Synthesis ,  OZOLA, Vita Latvian Institute of Organic Synthesis ,  SUNA, Edgars Latvian Inst. of Organic Synthesis ,  KALVINS, Ivars Latvian Inst. of Organic Synthesis ,  TRAPENCIERIS, Peteris Latvian Inst. of Organic Synthesis ,  KATKEVICA, Dace Latvian Inst. of Organic Synthesis ,  SCHAAL, Wesley

IPC分类号： C07D209/42 ,  A61P11/00 ,  A61P29/00 ,  A61K31/404 ,  C07D401/04 ,  C07D403/04 ,  C07D405/04 ,  C07D401/12

CPC分类号： C07D401/04 ,  C07D209/42 ,  C07D401/12 ,  C07D403/04 ,  C07D405/04

摘要： There is provided compounds of formula (I), wherein X1, Q, T, Y, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.