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1.发明公开POSITIVE ALLOSTERIC MODULATORS OF THE ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR AND USES THEREOF. 有权正变构调节烟碱型乙酰胆碱受体α及其用途7
公开(公告)号：EP2670731A1
公开(公告)日：2013-12-11
申请号：EP12741504.0
申请日：2012-02-02
申请人： Bionomics Limited
IPC分类号： C07C233/57 , A61P25/00 , C07C233/60 , A61K31/167 , A61P25/14 , C07D213/81 , A61K31/36 , A61P25/16 , C07D213/82 , A61K31/415 , A61P25/18 , C07D231/40 , A61K31/426 , A61P25/22 , C07D277/46 , A61K31/44 , A61P25/24 , C07D317/58 , A61K31/4409 , A61P25/28
CPC分类号： A61K31/4412 , A61K31/167 , A61K31/357 , A61K31/415 , A61K31/426 , A61K31/4409 , C07C233/59 , C07C233/60 , C07C311/16 , C07C311/46 , C07C2601/02 , C07C2602/50 , C07D209/46 , C07D213/75 , C07D231/40 , C07D275/06 , C07D277/46 , C07D317/46
摘要： The present invention relates to compounds useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (alpha7nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation of alpha7nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also inflammatory diseases.
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2.发明授权POSITIVE ALLOSTERIC MODULATORS OF THE ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR AND USES THEREOF. 有权正变构调节烟碱型乙酰胆碱受体α及其用途7
公开(公告)号：EP2670731B1
公开(公告)日：2016-05-25
申请号：EP12741504.0
申请日：2012-02-02
申请人： Bionomics Limited
IPC分类号： C07C233/57 , A61P25/00 , C07C233/60 , A61K31/167 , A61P25/14 , C07D213/81 , A61K31/36 , A61P25/16 , C07D213/82 , A61K31/415 , A61P25/18 , C07D231/40 , A61K31/426 , A61P25/22 , C07D277/46 , A61K31/44 , A61P25/24 , C07D317/58 , A61K31/4409 , A61P25/28
CPC分类号： A61K31/4412 , A61K31/167 , A61K31/357 , A61K31/415 , A61K31/426 , A61K31/4409 , C07C233/59 , C07C233/60 , C07C311/16 , C07C311/46 , C07C2601/02 , C07C2602/50 , C07D209/46 , C07D213/75 , C07D231/40 , C07D275/06 , C07D277/46 , C07D317/46
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