-
公开(公告)号:EP2814840B1
公开(公告)日:2019-11-13
申请号:EP12868427.1
申请日:2012-07-11
发明人: SCHELLENBERGER, Volker , CHANG, Pei-yun , VARFAJ, Fatbardha , DING, Sheng , SILVERMAN, Joshua , WANG, Chia-wei , SPINK, Benjamin , STEMMER, Willem, P. , GEETHING, Nathan , KULMAN, John , LIU, Tongyao , TOBY, Garabet, G. , JIANG, Haiyan , PETERS, Robert , WANG, Deping , MEI, Baisong
IPC分类号: C07K14/755 , A61K38/37 , A61K38/00
-
公开(公告)号:EP4194465A1
公开(公告)日:2023-06-14
申请号:EP22202315.2
申请日:2012-07-11
发明人: SCHELLENBERGER, Volker , CHANG, Pei-yun , VARFAJ, Fatbardha , DING, Sheng , SILVERMAN, Joshua , WANG, Chia-wei , SPINK, Benjamin , STEMMER, Willem P. , GEETHING, Nathan , KULMAN, John , LIU, Tongyao , TOBY, Garabet G. , JIANG, Haiyan , PETERS, Robert T. , WANG, Deping , MEI, Baisong
摘要: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor Vlll-related diseases, disorders, and conditions.
-