专利检索 ap:("Biscayne Neurotherapeutics, Inc.") AND inv:"GOLDSTEIN, Peter" 第 1 页

1.

发明公开
MODIFIED RELEASE PHARMACEUTICAL COMPOSITIONS OF HUPERZINE AND METHODS OF USING THE SAME 审中-公开

公开(公告)号：EP3624779A1

公开(公告)日：2020-03-25

申请号：EP18802748.6

申请日：2018-05-21

申请人： Biscayne Neurotherapeutics, Inc.

发明人： COLLINS, Stephen D. , GOLDSTEIN, Peter , JOHNSTONE, Joshua T.

IPC分类号： A61K9/20 , A61K31/4748 , A61K47/36

2.

发明公开
MODIFIED RELEASE PHARMACEUTICAL COMPOSITIONS OF HUPERZINE AND METHODS OF USING THE SAME 审中-实审

公开(公告)号：EP4327871A3

公开(公告)日：2024-06-05

申请号：EP23218583.5

申请日：2018-05-21

申请人： Biscayne Neurotherapeutics, Inc.

发明人： COLLINS, Stephen D. , GOLDSTEIN, Peter , JOHNSTONE, Joshua T.

IPC分类号： A61K9/20 , A61K31/4748 , A61K47/36 , A61K9/16 , A61K9/50 , A61K9/48 , A61P25/08

CPC分类号： A61K9/5078 , A61P25/08 , A61K31/4748 , A61K9/5047 , A61K9/4866

摘要： The present application discloses pharmaceutical compositions for modified release of huperzine. The pharmaceutical compositions and methods described herein, allow for dosing of huperzine at higher therapeutic thresholds, while avoiding rapid serum peak plasma levels, thereby avoiding the adverse nausea and vomiting associated with the immediate release pharmaceutical compositions. Methods of treating neurological disorders and/or seizure disorders with the modified release compositions is also described.