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公开(公告)号：EP3442958A1
公开(公告)日：2019-02-20
申请号：EP17715182.6
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton
IPC分类号： C07D401/12 , C07D213/82 , C07D213/84 , C07D413/12 , C07D417/12 , C07D487/04 , C07D213/64 , A61K31/4439 , A61K31/444 , A61K31/4402 , A61K31/44 , A61P25/00
摘要： This invention relates to compounds of formula (I), a process for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions having an association with the orexin sub-type 1 receptor. Ar, R1, R2, R3, R4, R5, R6 and R7 have meanings given in the description.
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公开(公告)号：EP3057963B1
公开(公告)日：2019-06-19
申请号：EP14784235.5
申请日：2014-10-15
IPC分类号： C07D413/14 , C07D409/06 , C07D409/14 , C07D417/14 , A61K31/496 , A61P25/18
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公开(公告)号：EP3442958B1
公开(公告)日：2020-05-06
申请号：EP17715182.6
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton
IPC分类号： C07D401/12 , C07D213/82 , C07D213/84 , C07D413/12 , C07D417/12 , C07D487/04 , C07D213/64 , A61K31/4439 , A61K31/444 , A61K31/4402 , A61K31/44 , A61P25/00
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公开(公告)号：EP3442963A1
公开(公告)日：2019-02-20
申请号：EP17715181.8
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton
IPC分类号： C07D403/12 , C07D413/12 , A61K31/497 , A61P25/00
摘要： This invention relates to compounds of formula (I) a process for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions having an association with the orexin sub-type 1 receptor. Ar, R1, R2 and R3 have meanings given in the description.
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公开(公告)号：EP3442967B1
公开(公告)日：2020-05-13
申请号：EP17717647.6
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton
IPC分类号： C07D403/12 , C07D413/12 , A61K31/506 , A61P25/00
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公开(公告)号：EP3442967A1
公开(公告)日：2019-02-20
申请号：EP17717647.6
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton
IPC分类号： C07D403/12 , C07D413/12 , A61K31/506 , A61P25/00
摘要： This invention relates to compounds of formula (I), a process for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions having an association with the orexin sub-type 1 receptor. Ar, R1, R2, R3, R4, R5 have meanings given in the description.
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公开(公告)号：EP3442965A1
公开(公告)日：2019-02-20
申请号：EP17716208.8
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton
IPC分类号： C07D403/12 , C07D401/14 , C07D413/14 , C07D213/81 , C07D401/12 , C07D239/34 , A61K31/444 , A61K31/506 , A61P25/00
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公开(公告)号：EP3442964A1
公开(公告)日：2019-02-20
申请号：EP17716207.0
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton , SCHEUERER, Stefan
IPC分类号： C07D403/12 , C07D401/14 , C07D401/12 , C07D239/42 , C07D413/12 , A61K31/506 , A61P25/00
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公开(公告)号：EP3442964B1
公开(公告)日：2020-05-06
申请号：EP17716207.0
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton , SCHEUERER, Stefan
IPC分类号： C07D403/12 , C07D401/14 , C07D401/12 , C07D239/42 , C07D413/12 , A61K31/506 , A61P25/00 , C07D403/04
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公开(公告)号：EP3442963B1
公开(公告)日：2020-05-06
申请号：EP17715181.8
申请日：2017-04-07
发明人： RIETHER, Doris , FERRARA, Marco , HEINE, Niklas , LESSEL, Uta , NICHOLSON, Janet Rachel , PEKCEC, Anton
IPC分类号： C07D403/12 , C07D413/12 , A61K31/497 , A61P25/00
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