公开(公告)号：EP1951894A4

公开(公告)日：2009-04-08

申请号：EP06705658

申请日：2006-02-20

申请人： CAPITALBIO CORP ,  UNIV TSINGHUA

发明人： GAO HUAFANG ,  LI ZE ,  WANG DONG ,  LIU YANHUA ,  LIU XIANG ,  JIANG YANGZHOU ,  ZHAO CHUANZAN ,  LI LI ,  LAN GENGXIN ,  GUO TAO ,  CAI BIN ,  XING WANLI ,  ZHOU YUXIANG ,  CHENG JING

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6837 ,  C12Q2600/156

摘要： The present invention provides a microarray for detecting a genotype at a polymorphic site in a plurality of nucleic acid samples, comprising a first set of nucleic acid fragments derived from the samples and a second set of nucleic acid fragments derived from a plurality of references immobilized thereon. The invention also provides a microarray comprising a set of nucleic acid fragments immobilized on the surface of the microarray, wherein the nucleic acid fragments are derived from the samples by amplifying a region in the sample containing the polymorphism through asymmetric PCR amplification. Methods of using and making the microarrays are also provided.

公开(公告)号：EP1981991A4

公开(公告)日：2010-01-13

申请号：EP07710869

申请日：2007-02-06

申请人： CAPITALBIO CORP ,  UNIV TSINGHUA

发明人： GAO HUAFANG ,  LI ZE ,  WANG DONG ,  LIU YANHUA ,  LIU XIANG ,  JIANG YANGZHOU ,  LI LI ,  ZHAO CHUANZAN ,  LAN GENGXIN ,  GUO TAO ,  CAI BIN ,  CHENG JING

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6832 ,  C12Q2600/156 ,  C12Q2535/131 ,  C12Q2527/107