公开(公告)号：EP1608321A2

公开(公告)日：2005-12-28

申请号：EP04759735.6

申请日：2004-03-24

申请人： CELL GENESYS, INC.

发明人： JOOSS, Karin ,  CRESON, Jennifer ,  LI, Betty ,  PRELL, Rodney ,  AUNG, Sandra ,  MOSKALENKO, Marina ,  DU, Thomas

IPC分类号： A61K7/00

CPC分类号： A61K39/0011 ,  A61K38/193 ,  A61K38/2013 ,  A61K38/212 ,  A61K2039/505 ,  A61K2039/5156 ,  A61K2039/5158 ,  C07K16/2818 ,  C07K16/2878 ,  A61K2300/00

摘要： The present invention in all of its associated aspects provides improved methods and compositions for treating cancer in a mammal based on the administration of the combination of a cytokine-expressing cellular vaccine and at least one additional cancer therapeutic agent or treatment to a patient with cancer, wherein administration of the combination results in enhanced therapeutic efficacy relative to administration of the cytokine-expressing cellular vaccine or cancer therapeutic agent or treatment as a monotherapy.