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1.发明公开METHOD AND MEANS FOR PRODUCING HIGH TITER, SAFE, RECOMBINANT LENTIVIRUS VECTORS 有权方法和装置，用于安全，重组慢病毒高滴度
公开(公告)号：EP1036182A1
公开(公告)日：2000-09-20
申请号：EP98962894.6
申请日：1998-12-11
申请人： CELL GENESYS, INC.
CPC分类号： C12N7/00 , A61K48/00 , C07K14/005 , C12N15/86 , C12N2740/11044 , C12N2740/16022 , C12N2740/16043 , C12N2740/16052
摘要： Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production.
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2.发明授权METHOD AND MEANS FOR PRODUCING HIGH TITER, SAFE, RECOMBINANT LENTIVIRUS VECTORS 有权方式和途径SAFE重组慢病毒载体高滴度生产
公开(公告)号：EP1171624B1
公开(公告)日：2007-07-25
申请号：EP00926354.2
申请日：2000-04-26
申请人： CELL GENESYS, INC.
IPC分类号： C12N15/867 , C12N15/63 , C12N15/64 , C12N15/48 , C12N15/86
CPC分类号： C12N15/86 , C12N2740/16043 , C12N2740/16045 , C12N2810/6081 , C12N2830/003
摘要： Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR are useful in the production of recombinant lentivirus vectors (See the Figure). Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production. The vectors can contain inducible or conditional promoters.
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3.发明授权METHOD AND MEANS FOR PRODUCING HIGH TITER, SAFE, RECOMBINANT LENTIVIRUS VECTORS 有权方法和装置，用于安全，重组慢病毒高滴度
公开(公告)号：EP1036182B1
公开(公告)日：2007-11-21
申请号：EP98962894.6
申请日：1998-12-11
申请人： CELL GENESYS, INC.
CPC分类号： C12N7/00 , A61K48/00 , C07K14/005 , C12N15/86 , C12N2740/11044 , C12N2740/16022 , C12N2740/16043 , C12N2740/16052
摘要： Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production.
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4.发明公开METHOD AND MEANS FOR PRODUCING HIGH TITER, SAFE, RECOMBINANT LENTIVIRUS VECTORS 有权方式和途径SAFE重组慢病毒载体高滴度生产
公开(公告)号：EP1171624A1
公开(公告)日：2002-01-16
申请号：EP00926354.2
申请日：2000-04-26
申请人： CELL GENESYS, INC.
IPC分类号： C12N15/867 , C12N15/63 , C12N15/64 , C12N15/48
CPC分类号： C12N15/86 , C12N2740/16043 , C12N2740/16045 , C12N2810/6081 , C12N2830/003
摘要： Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR are useful in the production of recombinant lentivirus vectors (See the Figure). Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production. The vectors can contain inducible or conditional promoters.
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