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公开(公告)号:EP1696952A1
公开(公告)日:2006-09-06
申请号:EP04815276.3
申请日:2004-12-21
申请人: CENTOCOR, INC.
发明人: DILLON, Susan, B. , DEL VECCHIO, Alfred, Michael , HUANG, Chichi , O'NEIL, Karyn, T. , SARISKY, Robert, T.
IPC分类号: A61K39/00 , A61K39/395 , A61K39/21
CPC分类号: C07K14/005 , C07K16/00 , C07K2317/52 , C07K2317/56 , C07K2319/00 , C07K2319/035 , C07K2319/31 , C07K2319/74 , C12N2740/16122 , C12N2740/16222
摘要: HIV gp41 mimetibody polypeptides and encoding polynucleotides are disclosed. Methods of utilizing the polypeptides to reduce or inhibit HIV fusion with a cell membrane and entry into target cells are also disclosed.