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1.发明公开
公开(公告)号：EP0930933A1
公开(公告)日：1999-07-28
申请号：EP98941547.0
申请日：1998-08-05
CPC分类号： A61K9/113 , B01D17/047 , B01F3/0811 , B01F2003/0826 , B01F2003/0838 , Y10S514/873 , Y10S514/885 , Y10S514/904 , Y10S514/913 , Y10S514/937 , Y10S514/938 , Y10S514/941 , Y10S514/942 , Y10S514/943 , Y10S514/969 , Y10S514/974 , Y10S514/975
摘要： The invention concerns a method for the controlled release of an active principle contained in a multiple water-in-oil-in-water emulsion characterised in that: said multiple emulsion comprises an invert emulsion Ei with a aqueous phase A1 containing at least a hydrophilic active principle, said emulsion Ei being dispersed in the form of direct emulsion droplets Ed, in a continuous aqueous phase A2, with the two emulsions Ed and Ei stabilised by at least a surfactant, present in their respective continuous phases; and said multiple emulsion is brought in the presence of an effective amount of an agent for transforming it into a direct emulsion and induce the release of the active principle, contained in the aqueous phase A1 of emulsion Ei, in the aqueous phase A2.
摘要翻译： 本发明涉及包含在多重水包油包水乳液中的活性成分受控释放的方法，其特征在于：所述多重乳液包含反相乳液Ei，其中含有至少含有亲水性活性成分 原理，所述乳液E 1以连续水相A 2分散成直接乳液液滴Ed的形式，两种乳液Ed和E i通过至少一种表面活性剂稳定化，存在于它们各自的连续相中; 并且所述多重乳液在有效量的试剂存在下转化成直接乳液并诱导包含在乳液Ei的水相A1中的活性成分释放到水相A2中。
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2.发明授权
公开(公告)号：EP0930933B1
公开(公告)日：2003-04-16
申请号：EP98941547.6
申请日：1998-08-05
IPC分类号： B01F17/00
CPC分类号： A61K9/113 , B01D17/047 , B01F3/0811 , B01F2003/0826 , B01F2003/0838 , Y10S514/873 , Y10S514/885 , Y10S514/904 , Y10S514/913 , Y10S514/937 , Y10S514/938 , Y10S514/941 , Y10S514/942 , Y10S514/943 , Y10S514/969 , Y10S514/974 , Y10S514/975
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