专利检索 ap:("CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)" OR "INSTITUT PASTEUR" OR "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)" OR "Université René Descartes") AND inv:"TROLLET, Capucine" 第 1 页

1.

发明公开
PROCÉDÉ D'IMMUNISATION GÉNÉTIQUE PAR ÉLECTROTRANSFERT CONTRE UNE TOXINE ET ANTISÉRUM SUSCEPTIBLE D'ÊTRE OBTENU PAR LEDIT PROCÉDÉ 审中-公开
标题翻译： PROCEDURE基因免疫电动TRANSFER针对毒素在这个过程中获得的抗血清

公开(公告)号：EP1906996A2

公开(公告)日：2008-04-09

申请号：EP06778059.3

申请日：2006-07-28

申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , INSTITUT PASTEUR , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , Université René Descartes

发明人： SCHERMAN, Daniel , BIGEY, Pascal , TROLLET, Capucine , POPOFF, Michel R. , PEREIRA, Yannick

IPC分类号： A61K39/08 , A61K31/7088

CPC分类号： A61K39/08 , A61K2039/53 , A61K2039/54

摘要： The invention concerns a method for obtaining an antiserum directed against a proteinic toxin by administering to an animal a solution comprising a genetic construct encoding a toxin immunogenic fragment, then applying an electric field in the administering zone, and isolating the serum. The invention also concerns the antiserum obtainable by the method as well as the use of the solution for making a medicine for preventing or treating a toxic effect related to absorption by a mammal of a toxin. The invention is characterized in that said medicine is formulated to be administered by electrotransfer.