-
1.发明授权FUSED BICYCLIC 2,4-DIAMINOPYRIMIDINE DERIVATIVE AS A DUAL ALK AND FAK INHIBITOR 有权稠合双环2,4-二氨基嘧啶衍生物作为双酯和FAK抑制剂
公开(公告)号：EP3056494B1
公开(公告)日：2018-05-02
申请号：EP15202516.9
申请日：2013-03-06
申请人： CEPHALON, INC.
IPC分类号： A61P35/00 , C07D403/04 , A61K31/506
CPC分类号： A61K31/506 , C07D403/04 , C07D403/12
摘要： The present invention provides a compound of formula (I) or a salt form thereof. The compound of formula (I) has ALK and FAK inhibitory activity, and may be used to treat proliferative disorders.
-
2.发明授权FUSED BICYCLIC 2,4-DIAMINOPYRIMIDINE DERIVATIVE AS A DUAL ALK AND FAK INHIBITOR 有权AS ALK和FAK双2,4-二氨基嘧啶稠合双环衍生物抑制剂
公开(公告)号：EP2822939B1
公开(公告)日：2016-02-17
申请号：EP13710258.8
申请日：2013-03-06
申请人： Cephalon, Inc.
IPC分类号： C07D403/04 , A61K31/506 , A61P9/00
CPC分类号： A61K31/506 , C07D403/04 , C07D403/12
-
3.发明公开FUSED BICYCLIC 2,4-DIAMINOPYRIMIDINE DERIVATIVE AS A DUAL ALK AND FAK INHIBITOR 有权AS ALK和FAK双2,4-二氨基嘧啶稠合双环衍生物抑制剂
公开(公告)号：EP2822939A1
公开(公告)日：2015-01-14
申请号：EP13710258.8
申请日：2013-03-06
申请人： Cephalon, Inc.
IPC分类号： C07D403/04 , A61K31/506 , A61P9/00
CPC分类号： A61K31/506 , C07D403/04 , C07D403/12
摘要： The present invention provides a compound of formula (I) or a salt form thereof. The compound of formula (I) has ALK and FAK inhibitory activity, and may be used to treat proliferative disorders.
-
公开(公告)号：EP2571885A1
公开(公告)日：2013-03-27
申请号：EP11721691.1
申请日：2011-05-17
申请人： Cephalon, Inc. , Cephalon France
IPC分类号： C07D487/14 , A61K31/506
CPC分类号： C07D487/14
摘要： The present invention relates a method for purifying a fused pyrrolocarbazole compound known as 11-isobutyl-2-methyl-8-(2-pyrimidinylamino)-2,5,6,11,12,13-hexahydro-4Hindazolo[5,4-a]pyrrolo [3,4-c]carbazol-4-one using an acid complex thereof. The present invention also relates to a crystalline form of the acid complex.
摘要翻译： 本发明涉及一种纯化称为11-异丁基-2-甲基-8-（2-嘧啶氨基）-2,5,6,11,12,13-六氢-4H-吲唑并[5,4- a]吡咯并[3,4-c]咔唑-4-酮。 本发明还涉及该酸性络合物的结晶形式。
-
5.发明公开FUSED BICYCLIC 2,4-DIAMINOPYRIMIDINE DERIVATIVE AS A DUAL ALK AND FAK INHIBITOR 有权KENENSIERTE BICYCLISCHE 2,4-二氨基嘧啶衍生物ALS-FAK-HEMMER
公开(公告)号：EP3056494A1
公开(公告)日：2016-08-17
申请号：EP15202516.9
申请日：2013-03-06
申请人： CEPHALON, INC.
IPC分类号： C07D403/04 , A61K31/506 , A61P9/00
CPC分类号： A61K31/506 , C07D403/04 , C07D403/12
摘要： The present invention provides a compound of formula (I)
or a salt form thereof. The compound of formula (I) has ALK and FAK inhibitory activity, and may be used to treat proliferative disorders.摘要翻译： 本发明提供式（I）化合物或其盐形式。 式（I）化合物具有ALK和FAK抑制活性，可用于治疗增殖性疾病。
-
公开(公告)号：EP2571885B1
公开(公告)日：2014-11-12
申请号：EP11721691.1
申请日：2011-05-17
申请人： Cephalon, Inc. , Teva Santé
IPC分类号： C07D487/14 , A61K31/506
CPC分类号： C07D487/14
-
7.发明授权SUBSTITUTED HEXAHYDROCHROMENO[3,4-B]PYRROLES WITH AFFINITY FOR THE SEROTONIN RECEPTOR (5-HT) FAMILY 有权取代HEXAHYDROCHROMENO [3,4-B]具有血清素受体的亲和力吡咯（5-HT）家族
公开(公告)号：EP2516446B1
公开(公告)日：2014-08-13
申请号：EP10801042.2
申请日：2010-12-17
申请人： Cephalon, Inc.
IPC分类号： C07D491/052 , A61K31/4439 , A61P25/00 , A61P1/00 , A61P3/00
CPC分类号： C07D491/052
-
8.发明公开SUBSTITUTED HEXAHYDROCHROMENO[3,4-B]PYRROLES WITH AFFINITY FOR THE SEROTONIN RECEPTOR (5-HT) FAMILY 有权取代HEXAHYDROCHROMENO [3,4-B]具有血清素受体的亲和力吡咯（5-HT）家族
公开(公告)号：EP2516446A2
公开(公告)日：2012-10-31
申请号：EP10801042.2
申请日：2010-12-17
申请人： Cephalon, Inc.
IPC分类号： C07D491/052 , A61K31/4439 , A61P25/00 , A61P1/00 , A61P3/00
CPC分类号： C07D491/052
摘要： This application relates to tricyclic compounds of Formula (I), including all stereoisomeric forms, all mixtures of stereoisomeric forms, and salts of these compounds. This application also relates to compositions comprising compounds of Formula (I), stereoisomeric forms, all mixtures of stereoisomeric forms, and salts thereof and uses therefor.
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.017 秒)
