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    ENHANCED ANTI-MICROBIAL PDT
    1.
    发明公开
    ENHANCED ANTI-MICROBIAL PDT 审中-公开
    高级抗菌PDT

    公开(公告)号：EP2542305A4

    公开(公告)日：2013-10-02

    申请号：EP11735020

    申请日：2011-01-13

    申请人： CERAMOPTEC GMBH

    发明人： ALBRECHT VOLKER ,  WIELAND GERHARD ,  GITTER BURKHARD ,  NEUBERGER WOLFGANG

    IPC分类号： A61N5/00 ,  A61K31/407 ,  A61L2/24 ,  A61N5/06 ,  A61P31/04

    CPC分类号： A61N5/062 ,  A61L2/0029 ,  A61L2/0052 ,  A61L2202/21 ,  A61M1/3681 ,  A61M1/3686 ,  A61N5/0624 ,  A61N2005/063 ,  A61N2005/0652

    摘要： Methods and devices to eliminate, reduce, destroy and/or inhibit undesired body fluid species, such as pathogen microbes and deteriorated or malignant cells in complex environments like blood, serum and other body fluids are provided. In preferred embodiments, an antimicrobial photodynamic therapy (PDT) treatment is given that effectively inactivates, reduces and/or destroys both Gram (−) and Gram (+) bacteria in complex body fluids. Methods to enhance antimicrobial PDT activity include administering a photosensitizer to bacteria-contaminated fluid, after a dwell time guiding bacteria-contaminated fluid with photosensitizer through a channel, emitting radiation preferably in an intermittent manner, and restoring treated body fluids to corresponding body regions. Electromagnetic radiation is preferably delivered intermittently with pulse width based on treatment parameters. Additionally, the method/device diminishes adverse host's inflammatory responses by neutralizing the biological activity of pathogenic microorganism fragments and reducing and/or removing pathogenic microorganism fragments responsible for it.

    DEVICE AND METHOD FOR UNDERSKIN RADIATION TREATMENT OF ADIPOSE TISSUE
    2.
    发明公开
    DEVICE AND METHOD FOR UNDERSKIN RADIATION TREATMENT OF ADIPOSE TISSUE 审中-公开
    VORRICHTUNG UND VERFAHREN ZUR UNTERHAUT-STRAHLUNGSBEHANDLUNG VON FETTGEWEBE

    公开(公告)号：EP2521591A4

    公开(公告)日：2013-05-29

    申请号：EP11732270

    申请日：2011-01-10

    申请人： CERAMOPTEC GMBH

    发明人： NEUBERGER WOLFGANG

    IPC分类号： A61B18/18 ,  A61N5/06 ,  A61N5/067

    CPC分类号： A61B18/22 ,  A61B2018/0019 ,  A61B2018/00994 ,  A61B2018/2005 ,  A61B2018/2272

    摘要： The device for carrying out underskin radiation treatment consists of a handpiece that allows easy manipulation by physicians, with a part that can be inserted below the skin and a part that can be held and manipulated outside the body. The part inserted below the skin can be vibrated or oscillated by means of suitable transducers to aid in distributing the radiation. Simultaneously or immediately afterwards, liquefied tissue is aspirated. If convenient, fluid irrigation of the area to be treated can be done. In a preferred embodiment, handpiece consists in a hollow cannula incorporating at least one channel for suction and/or irrigation and a light guiding means in its body/wall section for the purpose of the treatment and liquefaction of adipose tissue. The device further comprises at least one radiation source, included in device part affixed to the handpiece either in a permanent or detachable manner.

    摘要翻译： 公开了一种用于通过辐射能量源处理和去除脂肪组织的方法和装置。 公开的辐射辅助组织改良的方法包括将设备或部分皮肤下方的装置插入待治疗的区域，发射辐射并在组织区域内移动装置以达到所有部分。 该方法的特征在于以足够低的强度水平发射辐射，以实际上避免或最小化主要组织组分如脂肪和结缔组织中的碳化，但是具有足够的强度以使较小血管凝结，从而防止在所发射的光谱下出血。 因此，在优选实施例中，功率密度保持在高达约2W / mm。 这允许使用诸如400μm或更小的小直径纤维。 用于进行不透光治疗的装置包括一个手柄，其允许医生容易操作，其中一部分可以插入皮肤下面，并且可以在身体外部被保持和操纵的部分。 插入皮肤下方的部分可以通过合适的换能器振动或振荡，以帮助分布辐射。 同时或立即，抽出液化组织。 如果方便，可以进行待处理区域的流体灌溉。 在一个优选实施例中，手持件包括一个中空套管，其中包含至少一个用于抽吸和/或冲洗的通道，以及在其身体/壁部分中的导光装置，用于脂肪组织的处理和液化。 由于手机的特殊配置，可以使用各种各样的纤维尖端配置，即侧发射，锥形，径向发射，液滴形，反射盖，但不限于此。 每个纤维尖端配置允许最佳地执行不同的特定处理。 该装置还包括至少一个辐射源，包括在以永久或可拆卸的方式固定在手持件上的装置部件中。

    MEDICAL DEVICE RECOGNITION SYSTEM WITH WRITE-BACK FEATURE
    3.
    发明公开
    MEDICAL DEVICE RECOGNITION SYSTEM WITH WRITE-BACK FEATURE 审中-公开
    检测系统的回写功能的医疗装置

    公开(公告)号：EP1581129A4

    公开(公告)日：2010-12-22

    申请号：EP03790290

    申请日：2003-12-03

    申请人： CERAMOPTEC GMBH

    发明人： NEUBERGER WOLFGANG

    IPC分类号： A61B17/00 ,  A61B18/00 ,  A61B18/22 ,  A61B18/18

    CPC分类号： A61B18/22 ,  A61B90/90 ,  A61B2017/00482 ,  A61B2017/00725 ,  A61B2018/00988 ,  A61B2090/0803

    摘要： A medical radiation treatment system is disclosed for identifying and monitoring the use of disposable or reusable optical fibers or other optical accessories. The treatment system comprises a radiation source unit connected to a recognition/control unit, and a medical radiation delivery system connected to an identification/recordation unit. This forms a read-write system to ensure that radiation parameters conform to delivery device characteristics, and to prevent the use of overused or incompatible delivery devices. This is achieved by reading previously encoded information in the identification/recordation unit that provides all usage history, including number of uses or total duration of use. The encoded information is updated after use, and preferably frequently or continuously during use, to guarantee a complete usage history even after an incomplete treatment. Additionally, the treatment system can differentiate between completed treatments, incomplete treatments and calibration, to retain an accurate record of all the stresses on a fiber. A transponder sends information to the source unit, and also receives and writes information to a non-volatile memory chip or other storage means. The identification/recordation unit, including the transponder and memory, is powered by sending/receiving means in the recognition/control unit without physical, optical or electrical connection between the source unit and delivery system.

    TOPICAL APPLICATION OF CHROMOPHORES FOR HAIR REMOVAL
    5.
    发明公开
    TOPICAL APPLICATION OF CHROMOPHORES FOR HAIR REMOVAL 有权
    局部应用的发色团脱毛

    公开(公告)号：EP1439813A4

    公开(公告)日：2006-05-24

    申请号：EP02780381

    申请日：2002-09-26

    申请人： CERAMOPTEC GMBH

    发明人： SUMIAN CHRYSLAIN ,  NEUBERGER WOLFGANG ,  MORDON SERGE

    IPC分类号： A61N5/06 ,  A61K8/00 ,  A61K8/04 ,  A61K8/49 ,  A61Q5/00 ,  A61Q9/00 ,  A61Q9/04 ,  A61K7/15 ,  A61K7/155

    CPC分类号： A61Q9/04 ,  A61K8/0241 ,  A61K8/49 ,  A61K2800/412 ,  A61K2800/438 ,  A61K2800/56 ,  A61K2800/81 ,  A61K2800/82 ,  A61K2800/83 ,  A61Q9/00

    摘要： A device and method is disclosed for permanent or semi-permanent removal of hair through the activation of microparticles introduced into hair follicles. Microparticles are incorporated into a composition that is topically applied to the skin. These microparticles containing or consisting of chromophores or chemically activated molecules are of a variety of shapes and sizes. Microparticles are within a size range of 1 micron to 70 microns, and preferably between 10 and 50 microns. Microparticles of this size and variety of shapes enter hair follicles on all areas of the skin without entering other areas of the skin, such as the stratum corneum or sweat gland channels. Treatment of the skin with electromagnetic radiation, ultrasonic radiation or chemical means activates the chromophore or chemically activated compounds, thus destroying the hair follicle without damaging other areas of the skin. In another embodiment, microparticles further contain nanoparticles released further into the hair follicle by use of a solvent or other method, allowing chromophores or chemically activated molecules to penetrate deeper into the follicle and avoid structures such as the sebaceous gland.

    ACCURATE OPTICAL TREATMENT OF AN EYE'S FUNDUS
    9.
    发明公开
    ACCURATE OPTICAL TREATMENT OF AN EYE'S FUNDUS 审中-公开
    AN EYE背景的精确光学处理

    公开(公告)号：EP1309283A4

    公开(公告)日：2006-10-25

    申请号：EP01935141

    申请日：2001-05-08

    申请人： CERAMOPTEC GMBH

    发明人： PAWLOWSKI DIRK ,  NEUBERGER WOLFGANG

    IPC分类号： A61B3/135 ,  A61F9/008 ,  A61F9/009 ,  A61K41/00

    CPC分类号： A61F9/008 ,  A61B3/135 ,  A61F9/009 ,  A61F2009/00846 ,  A61F2009/00863 ,  A61K41/0042

    摘要： A system and method are provided to accurately treat sites on an eye's retina (2) employing computer based image generation, processing and central control means in conjunction with diode laser sources (14) and optical fibers. The system and method accurately determine geometry of a treatment zone of a specific eye's fundus and adjust a treatment beam to irradiate the treatment zone with minimal coverage of adjacent well tissue. The treatment zone or zone is accurately determined with digital processing (24) of angiographic data and slit lamp image data. This information is integrated with information on the treatment beam characteristics to better match treatment beam coverage with minimal overlap with healthy areas of the funds. Additionally preferred embodiments also have the ability to automatically track eye (1) movement and switch the beam source depending on eye movement, adjusting the beam spot area in real time.

    FREQUENCY CONVERSION COMBINER SYSTEM FOR DIODE LASERS
    10.
    发明公开
    FREQUENCY CONVERSION COMBINER SYSTEM FOR DIODE LASERS 审中-公开
    系统变频和聚焦激光二极管

    公开(公告)号：EP1090323A4

    公开(公告)日：2005-09-21

    申请号：EP99915335

    申请日：1999-04-08

    申请人： CERAMOPTEC GMBH

    发明人： NEUBERGER WOLFGANG ,  QUADE MICHAEL

    IPC分类号： G02B27/14 ,  G02F1/355 ,  H01S5/00 ,  H01S5/40 ,  G02F1/37 ,  H01S3/25

    CPC分类号： H01S5/4025 ,  H01S5/005 ,  H01S5/1014

    摘要： A frequency conversion diode beam combiner system is provided to multiplex several frequency converted laser beams and therefore keep the beam-quality of a single emitter. This multiplexing is physically impossible with free propagating beams. Both transformations, the frequency conversion and the beam multiplexing, must take place in one step in a single optical component or complex. This also aids the system to be very compact. The frequency conversion diode beam combiner system delivers a single beam which consists of several multiplexed beams from the converted radiation of the diode laser emitters. The high power high beam-quality of this device is not reachable with current diode lasers. A broad range of visible and infra-red wavelengths is possible. The frequency conversion diode beam combiner system can replace high power continuous wave (cw) solid state lasers, because its design is scaleable, small and simple.