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公开(公告)号:EP1908778A4
公开(公告)日:2009-08-12
申请号:EP06753060
申请日:2006-06-29
发明人: MA XIAOPENG , WANG BING , XI SHAOQI
IPC分类号: C07K14/575
CPC分类号: C07K14/57563 , A61K38/00
摘要: Exendin 4 polypeptide fragments having blood sugar lowering action which can be used for treating type II diabetes are provided. The polypeptide fragments have the sequence of HGEGTX1TSDLSKQX2EEEAVX3LFIEWLKNGX4PX5, wherein X1 represents Phe or Tyr, X2 represents Met, Ile or Leu, X3 represents Lys, X4 represents Gly or deletion, and X5 represents Arg or deletion. The process for preparing the Exendin 4 polypeptide fragments is also provided.