公开(公告)号：EP1260501A1

公开(公告)日：2002-11-27

申请号：EP02008248.3

申请日：2002-04-18

申请人： CHEMAGIS LTD.

发明人： Naddaka, Vladimir ,  Menashe, Naim ,  Lexner, Jael ,  Saeed, Shadi ,  Kaspi, Joseph ,  Leman, Ori

IPC分类号： C07C319/20 ,  C07C323/60

CPC分类号： C07C319/14 ,  C07C323/60

摘要： The invention provides a process for the preparation of diphenylmethylthioacetamide (I) as described in Scheme 4 comprising reacting of the isothiouronium salt or its corresponding base of the formula IV with an acetamide of the formula XCH 2 CONH 2 , wherein X represents a halogen, M represents an alkali metal and A represents an anion, in a protic medium at a temperature of less than 100° C.

摘要翻译： 本发明提供了如方案4所述的制备二苯基甲硫基乙酰胺（I）的方法，包括使异硫脲鎓盐或其相应的式IV碱与式XCH 2 CONH 2的乙酰胺反应，其中X代表卤素，M代表碱金属 金属和A代表阴离子，在温度低于100℃的质子介质中