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公开(公告)号:EP4130042A1
公开(公告)日:2023-02-08
申请号:EP21780305.5
申请日:2021-04-01
发明人: GUI, Qiu , ZHU, Hong , WANG, Liangliang , ZHANG, Xiaoyun , ZOU, Xiaofang , SHEN, Hengqiao , XU, Hongjiang , YANG, Ling
摘要: Provided are an antigen-binding polypeptide binding to CD47 or an antigen-binding portion thereof, nucleic acids encoding the polypeptide, vector, cell or pharmaceutical composition. The polypeptide can reduce a tumor or inhibit the growth of tumor cells, treat cancer, promote macrophage phagocytosis, and the like.