专利检索 ap:("CHIRON CORPORATION") AND inv:"HANSEN, Rhonda" 第 1 页

1.

发明公开
METHODS OF MODULATING METASTASIS AND SKELETAL RELATED EVENTS RESULTING FROM METASTASES 审中-公开
标题翻译：方法调制转移的关系，并与转移的基骨架相关事件

公开(公告)号：EP1628992A2

公开(公告)日：2006-03-01

申请号：EP04751974.9

申请日：2004-05-12

申请人： CHIRON CORPORATION

发明人： ZIMMERMAN, Deborah, Lee , HANSEN, Rhonda , WINTER, Jill , REINHARD, Christoph , FANG, Shuling

IPC分类号： C07H21/04 , A61K48/00 , C12Q1/68

CPC分类号： A61K31/663 , A61K31/7088 , A61K45/06 , A61K2300/00

摘要： The invention provides, inter alia, models of bone metastasis, methods for identifying agents that modulate skeletal related events and metastasis, methods for modulating skeletal related events and metastases, and methods for detecting skeletal related events and metastases. The methods and models generally comprise co-culturing cancer cells and host cells and comparing biological markers from such co-cultured cells to control cells.

2.

发明公开
GENE PRODUCTS DIFFERENTIALLY EXPRESSED IN CANCEROUS BREAST CELLS AND THEIR METHODS OF USE 有权
标题翻译：癌变MOM细胞中差异表达的基因产物及使用方法

公开(公告)号：EP1472375A1

公开(公告)日：2004-11-03

申请号：EP03729383.4

申请日：2003-01-08

申请人： Chiron Corporation

发明人： HANSEN, Rhonda

IPC分类号： C12Q1/68 , A01N43/04 , C07H21/04 , A61K31/07

CPC分类号： C07K16/3015 , A61K38/00 , C07K14/4748 , C12Q1/6837 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/57415 , G01N2500/10

摘要： The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in breast cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of breast cancer cells. These methods are useful for treating breast cancer.